1999
In Vivo Diffusion-Weighted Magnetic Resonance Microscopy of Rat Spinal Cord
Benveniste H, Qui H, Hedlund L, Hüttemeier P, Steele S, Johnson A. In Vivo Diffusion-Weighted Magnetic Resonance Microscopy of Rat Spinal Cord. Regional Anesthesia & Pain Medicine 1999, 24: 311-318. DOI: 10.1097/00115550-199924040-00006.Peer-Reviewed Original ResearchRat spinal cordSpinal cordHyperbaric 5Hyperbaric lidocaineNeurologic deficitsGroup 2Group 1Diffusion-weighted magnetic resonance microscopyWhite matterGray matterIrreversible neurologic deficitsPersistent neurologic deficitsSpinal cord ischemiaContinuous spinal anesthesiaPresence of ischemiaBlood-nerve barrierWhite matter tractsCord ischemiaIntrathecal anesthesiaIntrathecal lidocaineSpinal anesthesiaSpinal catheterPathophysiologic mechanismsCardiac arrestIrreversible conduction blockIn vivo diffusion-weighted magnetic resonance microscopy of rat spinal cord: Effect of ischemia and intrathecal hyperbaric 5% lidocaine
Benveniste H, Qui H, Hedlund L, Hüttemeier P, Steele S, Johnson G. In vivo diffusion-weighted magnetic resonance microscopy of rat spinal cord: Effect of ischemia and intrathecal hyperbaric 5% lidocaine. Regional Anesthesia & Pain Medicine 1999, 24: 311-318. PMID: 10445769, DOI: 10.1016/s1098-7339(99)90104-9.Peer-Reviewed Original ResearchConceptsDiffusion-weighted magnetic resonance microscopyRat spinal cordSpinal cordHyperbaric 5Hyperbaric lidocaineNeurologic deficitsGroup 2Group 1White matterGray matterIrreversible neurologic deficitsPersistent neurologic deficitsSpinal cord ischemiaContinuous spinal anesthesiaPresence of ischemiaBlood-nerve barrierEffects of ischemiaWhite matter tractsCord ischemiaIntrathecal anesthesiaIntrathecal lidocaineSpinal anesthesiaSpinal catheterPathophysiologic mechanismsCardiac arrest
1997
Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study
Qiu H, Hedlund L, Gewalt S, Benveniste H, Bare T, Johnson G. Progression of a focal ischemic lesion in rat brain during treatment with a novel glycine/nmda antagonist: An in vivo three‐dimensional diffusion‐weighted MR microscopy study. Journal Of Magnetic Resonance Imaging 1997, 7: 739-744. PMID: 9243396, DOI: 10.1002/jmri.1880070421.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryStroke volumeIpsilateral common carotid arteryReduced stroke volumeFocal ischemic lesionsCommon carotid arteryGlycine/NMDA antagonistsMCA occlusionCerebral arteryIschemic lesionsMultiple time pointsNMDA antagonistsCarotid arteryDrug treatmentRat brainGroup 2Group 1Control groupVivo studiesTime pointsZD9379ArteryOcclusionHoursTreatment