2023
Phenotyping Self-Reported Health Profiles in Octogenarians and Nonagenarians After Percutaneous Coronary Intervention: A Latent Profile Analysis
Instenes I, Breivik K, Borregaard B, Larsen A, Allore H, Bendz B, Deaton C, Rotevatn S, Norekvål T, investigators C. Phenotyping Self-Reported Health Profiles in Octogenarians and Nonagenarians After Percutaneous Coronary Intervention: A Latent Profile Analysis. Heart Lung And Circulation 2023, 32: 1321-1333. PMID: 37925313, DOI: 10.1016/j.hlc.2023.09.004.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionPoor health profileBetter health profileSelf-reported healthLow exercise levelsHealth profileCoronary interventionExercise levelsOlder adultsLow alcohol intakeLogistic regression analysisReal-world studyDifferent health outcomesMultinomial logistic regression analysisPatient characteristicsAlcohol intakeHealth outcomesHealth statusOctogenariansOlder ageNonagenariansMost participantsMonthsRegression analysisStandardised measuresRacial, ethnic, and socioeconomic disparities in trajectories of morbidity accumulation among older Americans
O'Neill A, Newsom J, Trubits E, Elman M, Botoseneanu A, Allore H, Nagel C, Dorr D, Quiñones A. Racial, ethnic, and socioeconomic disparities in trajectories of morbidity accumulation among older Americans. SSM - Population Health 2023, 22: 101375. PMID: 36941895, PMCID: PMC10024041, DOI: 10.1016/j.ssmph.2023.101375.Peer-Reviewed Original ResearchHispanic adultsRace/ethnicityBlack adultsWhite adultsMultiple chronic health conditionsNon-Hispanic white adultsNH White adultsChronic health conditionsSelf-reported morbidityCovariate-adjusted modelsPublic health interventionsProtective effectMorbidity countHealth interventionsPotential associationHealth disparitiesOlder ageSocioeconomic disparitiesHealth conditionsSocioeconomic statusSocioeconomic inequalitiesAdultsOlder AmericansRetirement StudyConsiderable heterogeneity
2022
Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study
Pettersen TR, Schjøtt J, Allore HG, Bendz B, Borregaard B, Fridlund B, Larsen AI, Nordrehaug JE, Rotevatn S, Wentzel-Larsen T, Norekvål TM. Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study. BMJ Open 2022, 12: e061689. PMID: 36127123, PMCID: PMC9490600, DOI: 10.1136/bmjopen-2022-061689.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionProspective multicentre cohort studyMulticentre cohort studyMedication adherenceCohort studyCoronary interventionFemale sexGeneric medicinesSelf-reported medication adherenceOlder ageSelf-reported health statusLow socioeconomic statusPoor mental healthLow education levelSecondary outcomesPCI centerBrand-name medicinesClinical variablesMean agePatients' perceptionsMAIN OUTCOMEHealth statusMental healthSocioeconomic statusTime pointsDiurnal effects of polypharmacy with high drug burden index on physical activities over 23 h differ with age and sex
Tran T, Mach J, Gemikonakli G, Wu H, Allore H, Howlett SE, Little CB, Hilmer SN. Diurnal effects of polypharmacy with high drug burden index on physical activities over 23 h differ with age and sex. Scientific Reports 2022, 12: 2168. PMID: 35140291, PMCID: PMC8828819, DOI: 10.1038/s41598-022-06039-4.Peer-Reviewed Original ResearchConceptsHigher Drug Burden IndexDrug Burden IndexBurden indexYoung miceOld micePhysical activityDifferent drug regimensWeeks of treatmentDrug-induced deliriumDaily physical activityTreatment × sex interactionBehavioral changesConsideration of ageSex-specific effectsSimvastatin monotherapyDrug regimensGait speedFunctional impairmentGlobal healthcare challengePolypharmacyQuality useOlder ageBehavioral declineMiceOlder adults