2020
Efficacy of telotristat ethyl: A peripheral tryptophan hydroxylase inhibitor that blocks serotonin biosynthesis against cultured liposarcoma, colon cancer, and cholangiocarcinoma cell lines.
Kliman H, Ling I, Milano K. Efficacy of telotristat ethyl: A peripheral tryptophan hydroxylase inhibitor that blocks serotonin biosynthesis against cultured liposarcoma, colon cancer, and cholangiocarcinoma cell lines. Journal Of Clinical Oncology 2020, 38: e15602-e15602. DOI: 10.1200/jco.2020.38.15_suppl.e15602.Peer-Reviewed Original ResearchTelotristat ethylTryptophan hydroxylase inhibitorCholangiocarcinoma cell linesCancer cell linesHydroxylase inhibitorColon cancerCell linesTE groupPR-positive breast cancerPositive breast cancerBlood-brain barrierCentral nervous systemLiposarcoma cell lineColon cancer cell linesLow power microscopic examinationPeripheral cancersCell line growthPositive cancersBrain barrierHT-29 cellsBreast cancerTPH inhibitorsCell confluenceNervous systemTumor cell line growth
1990
Aggregation of dispersed human cytotrophoblastic cells: Lessons relevant to the morphogenesis of the placenta
Babalola G, Coutifaris C, Soto E, Kliman H, Shuman H, Strauss J. Aggregation of dispersed human cytotrophoblastic cells: Lessons relevant to the morphogenesis of the placenta. Developmental Biology 1990, 137: 100-108. PMID: 2295358, DOI: 10.1016/0012-1606(90)90011-7.Peer-Reviewed Original ResearchConceptsJEG-3 cellsSuspension culturesCell-cell associationsJEG-3 choriocarcinoma cellsProtein synthesis inhibitorMulticellular structuresCellular aggregationHigh cell densityTrophoblast cell surfaceCytotrophoblast cellsHuman cytotrophoblastic cellsPlacenta formsCell typesRNA synthesisCell surfacePoor mediumChoriocarcinoma cellsCell linesSerum-free mediumActinomycin DOutgrowth culturesJEG-3Synthesis inhibitorExtent of aggregationFree medium