1997
EFFECT OF LONG-TERM ORAL L-ARGININE ON THE NITRIC OXIDE SYNTHASE PATHWAY IN THE URINE FROM PATIENTS WITH INTERSTITIAL CYSTITIS
Wheeler M, Smith S, Saito N, Foster H, Weiss R. EFFECT OF LONG-TERM ORAL L-ARGININE ON THE NITRIC OXIDE SYNTHASE PATHWAY IN THE URINE FROM PATIENTS WITH INTERSTITIAL CYSTITIS. Journal Of Urology 1997, 158: 2045-2050. PMID: 9366309, DOI: 10.1016/s0022-5347(01)68150-3.Peer-Reviewed Original ResearchConceptsInterstitial cystitis patientsNitric oxide synthase activityOral L-arginineOxide synthase activityInterstitial cystitisCystitis patientsL-arginineIL-8Oral L-arginine treatmentLong-term oral administrationInducible nitric oxide synthase (iNOS) proteinNitric oxideNitric oxide synthase proteinCyclic guanosine monophosphate levelsNitric oxide synthase pathwayUrinary nitric oxideInterstitial cystitis symptomsL-arginine treatmentInterleukin-8 levelsCytokine IL-8Nitric oxide synthaseSmooth muscle relaxationUrine of patientsGuanosine monophosphate levelsOxide synthase pathway
1996
Urinary Nitric Oxide Synthase Activity and Cyclic GMP Levels are Decreased with Interstitial Cystitis and Increased with Urinary Tract Infections
Smith S, Wheeler M, Foster H, Weiss R. Urinary Nitric Oxide Synthase Activity and Cyclic GMP Levels are Decreased with Interstitial Cystitis and Increased with Urinary Tract Infections. Journal Of Urology 1996, 155: 1432-1435. PMID: 8632605, DOI: 10.1016/s0022-5347(01)66301-8.Peer-Reviewed Original ResearchConceptsUrinary tract infectionCyclic GMP levelsUrinary nitric oxide synthase activityNitric oxide synthase activityInterstitial cystitisOxide synthase activityFemale patientsNOS activityTract infectionsGMP levelsFemale controlsFemale urinary tract infectionCyclic GMP/Certain disease processesIC patientsImmunologic responseUrinary tractSynthase activityDisease processL-argininePatientsNitric oxideL-citrullineGuanylyl cyclaseCyclic GMP