2006
Age‐related changes in the properties of α1‐adrenoceptors in the rat genitourinary tract
Yono M, Foster H, Yoshida M, Ueda S, Weiss R, Latifpour J. Age‐related changes in the properties of α1‐adrenoceptors in the rat genitourinary tract. The FASEB Journal 2006, 20: a254-a254. DOI: 10.1096/fasebj.20.4.a254-a.Peer-Reviewed Original ResearchLower urinary tract symptomsRat genitourinary tractBenign prostatic hyperplasiaΑ1-AR antagonistsAge-related changesMonth old ratsGenitourinary tractOld ratsBladder baseBladder domeDorsolateral prostateVentral prostateUrinary tract symptomsMaximum contractile responseLow testosterone levelsRadioligand receptor bindingSignificant age-dependent differencesReal-time RT-PCR techniqueAge-dependent differencesHigher body weightRT-PCR techniqueTract symptomsContractile responseOlder patientsSubtype mRNAs
2000
Expression of endothelin receptor subtypes and their messenger RNAs in diabetic rat prostate: Effect of insulin treatment
Saito M, Wado Y, Ikeda K, Wang Z, Foster H, Smith S, Weiss R, Latifpour J. Expression of endothelin receptor subtypes and their messenger RNAs in diabetic rat prostate: Effect of insulin treatment. Molecular And Cellular Biochemistry 2000, 210: 1-11. PMID: 10976752, DOI: 10.1023/a:1007041909477.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoradiographyBlood GlucoseBody WeightDiabetes Mellitus, ExperimentalEndothelin Receptor AntagonistsEndothelin-1InsulinIodine RadioisotopesMaleOrgan SizeProstateProtein IsoformsRadioligand AssayRandom AllocationRatsRats, Sprague-DawleyReceptor, Endothelin AReceptor, Endothelin BReceptors, EndothelinReverse Transcriptase Polymerase Chain ReactionRNA, MessengerTestosteroneUp-RegulationConceptsInduction of diabetesET receptorsReverse transcription-polymerase chain reactionRat prostateInsulin treatmentDiabetic animalsReceptor subtypesDiabetes-induced upregulationET receptor densityEndothelin receptor subtypesET receptor subtypesSTZ-injected ratsSerum testosterone levelsRadioligand receptor bindingDiabetic rat prostateTranscription-polymerase chain reactionDiabetic ratsETB receptorsSmaller prostatesEndothelin receptorsProstatic stromaTestosterone levelsReceptor densityPharmacological profileAutoradiographic study
1998
CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205. PMID: 9628650, DOI: 10.1016/s0022-5347(01)63090-8.Peer-Reviewed Original ResearchConceptsAlpha1 adrenoceptorsRabbit urethraMale rabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRabbit urethral smooth muscleUrethral smooth muscleRadioligand receptor bindingSmooth muscle actinSmooth muscle fibersLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistBMY 7378Distal urethraWB 4101Immunohistochemical studyPharmacological characterizationSmooth musclePharmacological profileAdrenoceptorsUrethraMuscle actinHigh-affinity binding sitesCHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA
NISHI K, LATIFPOUR J, SAITO M, FOSTER H, YOSHIDA M, WEISS R. CHARACTERIZATION, LOCALIZATION AND DISTRIBUTION OF alpha1 ADRENOCEPTOR SUBTYPE IN MALE RABBIT URETHRA. Journal Of Urology 1998, 160: 196-205.. DOI: 10.1097/00005392-199807000-00084.Peer-Reviewed Original ResearchAlpha1 adrenoceptorsMale rabbit urethraRabbit urethraSelective alpha1-adrenoceptor antagonistAnti-alpha smooth muscle actinAlpha1-adrenoceptor antagonistRadioligand receptor bindingSmooth muscle actinLight microscopic autoradiographySingle high-affinity binding siteAdrenoceptor antagonistPharmacological profileAbstract PurposeMuscle actinHigh-affinity binding sitesUrethraSubtype specificityAdrenoceptorsAffinity binding sitesReceptor bindingActin antibodyMicroscopic autoradiographySaturation experimentsInhibition experimentsRank order