2022
Association of Neighborhood-Level Material Deprivation With Atrial Fibrillation Care in a Single-Payer Health Care System: A Population-Based Cohort Study
Abdel-Qadir H, Akioyamen LE, Fang J, Pang A, Ha ACT, Jackevicius CA, Alter DA, Austin PC, Atzema CL, Bhatia RS, Booth GL, Johnston S, Dhalla I, Kapral MK, Krumholz HM, McNaughton CD, Roifman I, Tu K, Udell JA, Wijeysundera HC, Ko DT, Schull MJ, Lee DS. Association of Neighborhood-Level Material Deprivation With Atrial Fibrillation Care in a Single-Payer Health Care System: A Population-Based Cohort Study. Circulation 2022, 146: 159-171. PMID: 35678171, PMCID: PMC9287095, DOI: 10.1161/circulationaha.122.058949.Peer-Reviewed Original ResearchConceptsYears of ageCohort studyUniversal health careAF-related adverse eventsNeighbourhood-level material deprivationPopulation-based cohort studyPrimary care physician visitsCause-specific hazards regressionRhythm control interventionsHigh cardiovascular disease burdenCardiovascular disease burdenHealth careAtrial fibrillation careNeighborhood material deprivationSingle-payer health care systemMaterial deprivation quintileAtrial fibrillation diagnosisHealth care systemNoncardiovascular comorbiditiesAdverse eventsHeart failurePhysician visitsHazards regressionAdverse outcomesDeprivation quintilePerspectives of Patients About Artificial Intelligence in Health Care
Khullar D, Casalino LP, Qian Y, Lu Y, Krumholz HM, Aneja S. Perspectives of Patients About Artificial Intelligence in Health Care. JAMA Network Open 2022, 5: e2210309. PMID: 35507346, PMCID: PMC9069257, DOI: 10.1001/jamanetworkopen.2022.10309.Peer-Reviewed Original Research
2020
Quality of primary health care in China: challenges and recommendations
Li X, Krumholz HM, Yip W, Cheng KK, De Maeseneer J, Meng Q, Mossialos E, Li C, Lu J, Su M, Zhang Q, Xu DR, Li L, Normand ST, Peto R, Li J, Wang Z, Yan H, Gao R, Chunharas S, Gao X, Guerra R, Ji H, Ke Y, Pan Z, Wu X, Xiao S, Xie X, Zhang Y, Zhu J, Zhu S, Hu S. Quality of primary health care in China: challenges and recommendations. The Lancet 2020, 395: 1802-1812. PMID: 32505251, PMCID: PMC7272159, DOI: 10.1016/s0140-6736(20)30122-7.Peer-Reviewed Original ResearchConceptsPrimary health care systemHealth care systemPrimary health carePublic health servicesClinical careHealth servicesPrimary health care physiciansPrimary health care practitionersPrimary health care institutionsBasic public health servicesHealth care physiciansHealth careCoronavirus disease 2019Entire health care systemHealth care practitionersHigh-value careLearning health systemChronic diseasesDisease 2019Health care institutionsInfectious diseasesHealth systemCare systemCareSuboptimal education
2018
Geographical Health Priority Areas For Older Americans
Krumholz HM, Normand ST, Wang Y. Geographical Health Priority Areas For Older Americans. Health Affairs 2018, 37: 104-110. PMID: 29309217, DOI: 10.1377/hlthaff.2017.0744.Peer-Reviewed Original ResearchConceptsHealth priority areasMortality rateHigher adjusted mortality ratesRisk-standardized mortality ratesAdjusted mortality rateHealth careUnique Medicare beneficiariesMedicare beneficiariesUS populationHealth disparitiesOlder adultsStudy periodGeographic disparitiesOlder AmericansCarePercentDisparitiesPriority areasWide disparity
2017
Availability, cost, and prescription patterns of antihypertensive medications in primary health care in China: a nationwide cross-sectional survey
Su M, Zhang Q, Bai X, Wu C, Li Y, Mossialos E, Mensah GA, Masoudi FA, Lu J, Li X, Salas-Vega S, Zhang A, Lu Y, Nasir K, Krumholz HM, Jiang L. Availability, cost, and prescription patterns of antihypertensive medications in primary health care in China: a nationwide cross-sectional survey. The Lancet 2017, 390: 2559-2568. PMID: 29102087, DOI: 10.1016/s0140-6736(17)32476-5.Peer-Reviewed Original ResearchConceptsPrimary health care sitesNationwide cross-sectional surveyAntihypertensive medicationsPrimary health carePrescription patternsCross-sectional surveyHealth care sitesHealth centersVillage clinicsPrimary health care providersCommunity health stationsBurden of hypertensionCommunity health centersHealth careCAMS Innovation FundHealth care providersHigh-cost medicationsTownship health centersBlood pressureFamily Planning CommissionMedication costsAffordable medicationsNational HealthHealth stationsMedicationsQuality of Care in the United States Territories, 1999–2012
Nuti SV, Wang Y, Masoudi FA, Nunez-Smith M, Normand ST, Murugiah K, Rodríguez-Vilá O, Ross JS, Krumholz HM. Quality of Care in the United States Territories, 1999–2012. Medical Care 2017, 55: 886-892. PMID: 28906314, PMCID: PMC6482857, DOI: 10.1097/mlr.0000000000000797.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failureHospitalization ratesMedicare beneficiariesMortality rateService Medicare beneficiariesQuality of careRecent study periodPneumonia hospitalizationsMyocardial infarctionPatient outcomesMillions of AmericansMedicare feeHealth outcomesPneumoniaService beneficiariesHospital reimbursementUnique beneficiariesHealth equityStudy periodPatient paymentsInpatient paymentsHealth careMortalityCareProtocol for a nationwide survey of primary health care in China: the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) MPP (Million Persons Project) Primary Health Care Survey
Su M, Zhang Q, Lu J, Li X, Tian N, Wang Y, Yip W, Cheng KK, Mensah GA, Horwitz RI, Mossialos E, Krumholz HM, Jiang L. Protocol for a nationwide survey of primary health care in China: the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) MPP (Million Persons Project) Primary Health Care Survey. BMJ Open 2017, 7: e016195. PMID: 28851781, PMCID: PMC5629739, DOI: 10.1136/bmjopen-2017-016195.Peer-Reviewed Original ResearchConceptsPrimary health careMillion Persons ProjectQuality of careCardiac Events Million Persons ProjectHealth carePrimary care servicesEssential medicines programmeHealth Care SurveyChina PatientCare SurveyPatient satisfactionPHC servicesPHC workforceCardiovascular diseaseCare servicesObservational designPHC institutionsCentral Ethics CommitteeInformed consentChina National CenterEthics CommitteeCarePerson interviewsMedicine programsNationwide survey
2016
Sex Differences in Financial Barriers and the Relationship to Recovery After Acute Myocardial Infarction
Beckman AL, Bucholz EM, Zhang W, Xu X, Dreyer RP, Strait KM, Spertus JA, Krumholz HM, Spatz ES. Sex Differences in Financial Barriers and the Relationship to Recovery After Acute Myocardial Infarction. Journal Of The American Heart Association 2016, 5: e003923. PMID: 27742618, PMCID: PMC5121496, DOI: 10.1161/jaha.116.003923.Peer-Reviewed Original ResearchMeSH KeywordsAdultAftercareDepressionDrug CostsFemaleHealth Services AccessibilityHumansIncomeLinear ModelsMaleMedication AdherenceMiddle AgedMultivariate AnalysisMyocardial InfarctionPatient Health QuestionnaireProspective StudiesRecovery of FunctionSex FactorsSocioeconomic FactorsSpainUnited StatesConceptsAcute myocardial infarctionMyocardial infarctionFinancial barriersHealth status 12 monthsYoung adultsPost-AMI outcomesYear post-AMIYoung AMI patientsMultivariable linear regression modelsGreater depressive symptomatologyMental functional statusSex differencesClinical characteristicsYounger patientsAMI patientsPost-AMIFunctional statusWorse outcomesBaseline healthPsychosocial statusOutcomes 1Depressive symptomatologyPatientsMore womenHealth careData Acquisition, Curation, and Use for a Continuously Learning Health System: A Vital Direction for Health and Health Care
Krumholz H, Bourne P, Kuntz R, Paz H, Terry S, Waldstreicher J. Data Acquisition, Curation, and Use for a Continuously Learning Health System: A Vital Direction for Health and Health Care. NAM Perspectives 2016, 6 DOI: 10.31478/201609w.Peer-Reviewed Original Research
2015
Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013
Krumholz HM, Nuti SV, Downing NS, Normand SL, Wang Y. Mortality, Hospitalizations, and Expenditures for the Medicare Population Aged 65 Years or Older, 1999-2013. JAMA 2015, 314: 355-365. PMID: 26219053, PMCID: PMC5459402, DOI: 10.1001/jama.2015.8035.Peer-Reviewed Original ResearchConceptsMonths of lifeMedicare beneficiariesService beneficiariesMedicare feeInpatient expendituresCause mortalitySerial cross-sectional analysisCause mortality ratesNumber of hospitalizationsIntensity of careUnique Medicare beneficiariesCross-sectional analysisPercentage of beneficiariesCause hospitalizationTotal hospitalizationsMore hospitalizationsHospitalization ratesMedicare denominatorInpatient filesHospitalizationMAIN OUTCOMEMortality rateMortalityHealth careKey demographic groups
2014
Approaches to Enhancing Radiation Safety in Cardiovascular Imaging
Fazel R, Gerber TC, Balter S, Brenner DJ, Carr JJ, Cerqueira MD, Chen J, Einstein AJ, Krumholz HM, Mahesh M, McCollough CH, Min JK, Morin RL, Nallamothu BK, Nasir K, Redberg RF, Shaw LJ. Approaches to Enhancing Radiation Safety in Cardiovascular Imaging. Circulation 2014, 130: 1730-1748. PMID: 25366837, DOI: 10.1161/cir.0000000000000048.Peer-Reviewed Original Research
2011
Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004
Cherlin EJ, Allam AA, Linnander EL, Wong R, El-Toukhy E, Sipsma H, Krumholz HM, Curry LA, Bradley EH. Inputs to quality: supervision, management, and community involvement in health facilities in Egypt in 2004. BMC Health Services Research 2011, 11: 282. PMID: 22014078, PMCID: PMC3216250, DOI: 10.1186/1472-6963-11-282.Peer-Reviewed Original ResearchConceptsHealth unitsMiddle-income countriesHealth facilitiesHealth Survey websiteService Provision Assessment surveyMinority of facilitiesQuality improvement initiativesRural health unitsUrban health unitsCross-sectional analysisHealth care deliveryMinistry of HealthHealth reformMeasure DemographicFinal sampleGeneral service hospitalsMore rural partsService hospitalsChild healthStandard frequency analysisCare deliveryFacility characteristicsHealth careStatistical significanceImprovement initiativesTrailblazer for Patient-Centered Care
Krumholz H. Trailblazer for Patient-Centered Care. Science 2011, 331: 1138-1138. DOI: 10.1126/science.1198393.Peer-Reviewed Original Research
2010
Racial Disparities in Health Literacy and Access to Care Among Patients With Heart Failure
Chaudhry SI, Herrin J, Phillips C, Butler J, Mukerjhee S, Murillo J, Onwuanyi A, Seto TB, Spertus J, Krumholz HM. Racial Disparities in Health Literacy and Access to Care Among Patients With Heart Failure. Journal Of Cardiac Failure 2010, 17: 122-127. PMID: 21300301, PMCID: PMC3053061, DOI: 10.1016/j.cardfail.2010.09.016.Peer-Reviewed Original ResearchConceptsHeart failure patientsHealth literacyFailure patientsHeart failureInsurance statusWorse health literacyOutpatient medical careRacial differencesImportant racial differencesNoncardiac comorbiditiesUnadjusted analysesBlack raceCare existMedical homePatientsMedical careRacial disparitiesSocioeconomic statusStrong associationPotential mediatorsHealth carePoor accessCareSocial supportStatus
2008
Hospital Remoteness And Thirty-Day Mortality From Three Serious Conditions
Ross JS, Normand SL, Wang Y, Nallamothu BK, Lichtman JH, Krumholz HM. Hospital Remoteness And Thirty-Day Mortality From Three Serious Conditions. Health Affairs 2008, 27: 1707-1717. PMID: 18997230, DOI: 10.1377/hlthaff.27.6.1707.Peer-Reviewed Original ResearchConceptsRisk-standardized mortality ratesThirty-day mortalityAcute myocardial infarctionHigh-quality health careMedicare administrative dataGeographic remotenessHeart failureMyocardial infarctionSerious conditionMillions of AmericansRural U.S. communitiesMortality differencesMortality rateRural hospitalsSmaller mortality differencesHealth careAdministrative dataHospitalU.S. communitiesCareHospitalizationInfarctionPneumoniaMortality
2007
Financial Barriers to Health Care and Outcomes After Acute Myocardial Infarction
Rahimi AR, Spertus JA, Reid KJ, Bernheim SM, Krumholz HM. Financial Barriers to Health Care and Outcomes After Acute Myocardial Infarction. JAMA 2007, 297: 1063-1072. PMID: 17356027, DOI: 10.1001/jama.297.10.1063.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHealth care servicesCare servicesMyocardial infarctionCardiac rehospitalizationSAQ qualityCause rehospitalizationLife scoresFinancial barriersMulticenter US studyHealth care outcomesProspective registryBaseline prevalenceRehospitalizationHigh riskMedicationsCare outcomesWorse recoveryInfarctionPrevalenceHealth careUS studiesPatientsPoor qualityOutcomes
2006
Prevalence, Predictors, and Outcomes of Premature Discontinuation of Thienopyridine Therapy After Drug-Eluting Stent Placement
Spertus JA, Kettelkamp R, Vance C, Decker C, Jones PG, Rumsfeld JS, Messenger JC, Khanal S, Peterson ED, Bach RG, Krumholz HM, Cohen DJ. Prevalence, Predictors, and Outcomes of Premature Discontinuation of Thienopyridine Therapy After Drug-Eluting Stent Placement. Circulation 2006, 113: 2803-2809. PMID: 16769908, DOI: 10.1161/circulationaha.106.618066.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngioplasty, Balloon, CoronaryCardiovascular AgentsCause of DeathClopidogrelCombined Modality TherapyCoronary RestenosisDrug Administration ScheduleDrug ImplantsFemaleFollow-Up StudiesHospitalizationHumansLife TablesMaleMiddle AgedMortalityMyocardial InfarctionPatient Education as TopicPlatelet Aggregation InhibitorsPrevalenceProportional Hazards ModelsProspective StudiesPyridinesRegistriesSirolimusStentsSurvival AnalysisThrombosisTiclopidineTreatment OutcomeTreatment RefusalConceptsDrug-eluting stentsThienopyridine therapyMI patientsMyocardial infarctionCardiac rehabilitation referralUse of thienopyridinesAcute myocardial infarctionPremature discontinuationDES placementRehabilitation referralHospitalization ratesStent thrombosisDischarge instructionsStent placementCardiovascular diseaseSubsequent mortalityPatientsDES treatmentTherapyHealth careMonthsThienopyridinesMortalityPrevalenceDays
2004
Differences, disparities, and biases: clarifying racial variations in health care use.
Rathore SS, Krumholz HM. Differences, disparities, and biases: clarifying racial variations in health care use. Annals Of Internal Medicine 2004, 141: 635-8. PMID: 15492343, DOI: 10.7326/0003-4819-141-8-200410190-00011.Peer-Reviewed Original ResearchConceptsHealth care useCare useRacial variationRacial differencesHealth care system factorsAdverse consequencesClinical factorsClinical contraindicationsTreatment eligibilityPatient preferencesObservational studyEvidence of differencesMedical literatureRacial disparitiesHealth careInitial reportSystem factorsDifferent causesTreatmentReports of variationReportDisparitiesContraindicationsDifferencesCare
2000
Medicare Initiatives to Improve Heart Failure Care: An Introduction
Ordin D, Masoudi F, Havranek E, Krumholz H. Medicare Initiatives to Improve Heart Failure Care: An Introduction. Congestive Heart Failure 2000, 6: 280-282. PMID: 12189290, DOI: 10.1111/j.1527-5299.2000.80166.x.Peer-Reviewed Original ResearchHeart failure patientsHeart failureFailure patientsHeart Failure Practice Improvement EffortCommon discharge diagnosesLittle national informationOutcomes of patientsHeart failure careHealth careCare of patientsPractice improvement effortsQuality improvement projectContinuum of careHealth care professionalsHealth Care Financing AdministrationQuality of careQuality improvement effortsGuideline recommendationsDischarge diagnosisInpatient careMedicare beneficiariesCare professionalsPatientsImprovement effortsCare