2024
Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic
Faust J, Renton B, Bongiovanni T, Chen A, Sheares K, Du C, Essien U, Fuentes-Afflick E, Haywood T, Khera R, King T, Li S, Lin Z, Lu Y, Marshall A, Ndumele C, Opara I, Loarte-Rodriguez T, Sawano M, Taparra K, Taylor H, Watson K, Yancy C, Krumholz H. Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic. JAMA Network Open 2024, 7: e2438918. PMID: 39392630, PMCID: PMC11581672, DOI: 10.1001/jamanetworkopen.2024.38918.Peer-Reviewed Original ResearchConceptsCOVID-19 public health emergencyNon-HispanicPublic health emergencyOther Pacific IslanderExcess mortalityAlaska NativesUS populationExcess deathsRates of excess mortalityCross-sectional study analyzed dataYears of potential lifeMortality relative riskNon-Hispanic whitesCross-sectional studyPacific IslandersStudy analyzed dataAll-cause mortalityEthnic groupsMortality disparitiesMortality ratioTotal populationDeath certificatesEthnic disparitiesMain OutcomesDecedent age
2023
State-Level Excess Mortality and Potential Deaths Averted in US Adults During the Delta and Omicron Waves of COVID-19
Renton B, Du C, Chen A, Li S, Lin Z, Krumholz H, Faust J. State-Level Excess Mortality and Potential Deaths Averted in US Adults During the Delta and Omicron Waves of COVID-19. Journal Of General Internal Medicine 2023, 39: 142-146. PMID: 37620716, PMCID: PMC10817860, DOI: 10.1007/s11606-023-08374-2.Peer-Reviewed Original ResearchExcess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020
Caraballo C, Massey D, Ndumele C, Haywood T, Kaleem S, King T, Liu Y, Lu Y, Nunez-Smith M, Taylor H, Watson K, Herrin J, Yancy C, Faust J, Krumholz H. Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020. JAMA 2023, 329: 1662-1670. PMID: 37191702, PMCID: PMC10189563, DOI: 10.1001/jama.2023.7022.Peer-Reviewed Original ResearchConceptsExcess mortality ratesExcess deathsMortality ratePotential lifeWhite populationExcess mortalitySerial cross-sectional studyHighest excess mortality ratesBlack populationCause-specific mortalityCross-sectional studyHigh mortality rateNon-Hispanic whitesYears of lifeUS national dataMiddle-aged adultsCause mortalityHeart diseaseDeath certificatesNon-Hispanic black populationMAIN OUTCOMEAge groupsDisease controlMortalityBlack males
2022
Leading Causes of Death Among Adults Aged 25 to 44 Years by Race and Ethnicity in Texas During the COVID-19 Pandemic, March to December 2020
Faust JS, Chen AJ, Tiako M, Du C, Li SX, Krumholz HM, Barnett ML. Leading Causes of Death Among Adults Aged 25 to 44 Years by Race and Ethnicity in Texas During the COVID-19 Pandemic, March to December 2020. JAMA Internal Medicine 2022, 182: 87-90. PMID: 34807250, PMCID: PMC8609460, DOI: 10.1001/jamainternmed.2021.6734.Peer-Reviewed Original Research
2021
Disparities in Excess Mortality Associated with COVID-19 — United States, 2020
Rossen LM, Ahmad FB, Anderson RN, Branum AM, Du C, Krumholz HM, Li SX, Lin Z, Marshall A, Sutton PD, Faust JS. Disparities in Excess Mortality Associated with COVID-19 — United States, 2020. MMWR Morbidity And Mortality Weekly Report 2021, 70: 1114-1119. PMID: 34411075, PMCID: PMC8375709, DOI: 10.15585/mmwr.mm7033a2.Peer-Reviewed Original ResearchConceptsMortality incidence ratesIncidence rateExcess mortalityAge groupsHighest excess mortality ratesExcess Mortality AssociatedGreater excess mortalityExcess mortality ratesAI/AN populationsNon-Hispanic American IndianNon-Hispanic blacksNational Vital Statistics SystemCOVID-19 pandemicPublic health messagingNon-Hispanic white populationRace/ethnicityVital Statistics SystemMortality AssociatedLack of adjustmentMortality rateExcess deathsAN populationsEthnic groupsHealth messagingHispanic personsMortality From Drug Overdoses, Homicides, Unintentional Injuries, Motor Vehicle Crashes, and Suicides During the Pandemic, March-August 2020
Faust JS, Du C, Mayes KD, Li SX, Lin Z, Barnett ML, Krumholz HM. Mortality From Drug Overdoses, Homicides, Unintentional Injuries, Motor Vehicle Crashes, and Suicides During the Pandemic, March-August 2020. JAMA 2021, 326: 84-86. PMID: 34019096, PMCID: PMC8140390, DOI: 10.1001/jama.2021.8012.Peer-Reviewed Original ResearchAll-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020
Faust JS, Krumholz HM, Du C, Mayes KD, Lin Z, Gilman C, Walensky RP. All-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020. JAMA 2021, 325: 785-787. PMID: 33325994, PMCID: PMC7745134, DOI: 10.1001/jama.2020.24243.Peer-Reviewed Original Research
2006
Renal Impairment and Outcomes in Heart Failure Systematic Review and Meta-Analysis
Smith GL, Lichtman JH, Bracken MB, Shlipak MG, Phillips CO, DiCapua P, Krumholz HM. Renal Impairment and Outcomes in Heart Failure Systematic Review and Meta-Analysis. Journal Of The American College Of Cardiology 2006, 47: 1987-1996. PMID: 16697315, DOI: 10.1016/j.jacc.2005.11.084.Peer-Reviewed Original ResearchConceptsRenal impairmentHF patientsSevere impairmentRenal functionExcess mortalityMortality riskSystematic reviewAssociated mortality riskHeart failure patientsCause mortality riskPrecise risk estimatesCause mortalityFailure patientsDL increaseRisk stratificationTherapeutic strategiesPatientsMeta-AnalysisMortalityRisk estimatesImpairmentSystematic searchMin decreaseRiskCreatinine
2001
Quality of Medical Care and Excess Mortality in Older Patients With Mental Disorders
Druss BG, Bradford WD, Rosenheck RA, Radford MJ, Krumholz HM. Quality of Medical Care and Excess Mortality in Older Patients With Mental Disorders. JAMA Psychiatry 2001, 58: 565-572. PMID: 11386985, DOI: 10.1001/archpsyc.58.6.565.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAngiotensin-Converting Enzyme InhibitorsAspirinCluster AnalysisCohort StudiesComorbidityFemaleFollow-Up StudiesHospitalizationHumansMaleMedicareMental DisordersMyocardial InfarctionMyocardial ReperfusionProportional Hazards ModelsQuality of Health CareRisk FactorsSmoking CessationVentricular Function, LeftConceptsExcess mortalityMajor affective disordersMyocardial infarctionMedical careMental disordersAffective disordersMedicare patients 65 yearsCardiac risk factorsPatients 65 yearsAcute myocardial infarctionProportional hazards modelPatient's medical carePotential confounding factorsCessation counselingOlder patientsVentricular functionAdmission characteristicsNational cohortHospital characteristicsRisk factorsHazards modelEnzyme inhibitorsConfounding factorsMortalityInfarction
2000
Care and outcomes of elderly patients with acute myocardial infarction by physician specialty: the effects of comorbidity and functional limitations
Chen J, Radford M, Wang Y, Krumholz H. Care and outcomes of elderly patients with acute myocardial infarction by physician specialty: the effects of comorbidity and functional limitations. The American Journal Of Medicine 2000, 108: 460-469. PMID: 10781778, DOI: 10.1016/s0002-9343(00)00331-4.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedCardiologyComorbidityFamily PracticeFemaleGeriatric AssessmentHospital MortalityHospitalizationHumansInternal MedicineMaleMedicareMyocardial InfarctionPractice Guidelines as TopicPractice Patterns, Physicians'Quality Indicators, Health CareRetrospective StudiesSeverity of Illness IndexSurvival AnalysisTreatment OutcomeUnited StatesConceptsAcute myocardial infarctionMyocardial infarctionGeneral practitionersPhysician specialtyFunctional limitationsComorbid illnessesPatient characteristicsSurvival benefitComorbid conditionsCardiology careNational Cooperative Cardiovascular ProjectEffect of comorbidityCooperative Cardiovascular ProjectBoard-certified cardiologistsInternal medicine subspecialistsMost comorbiditiesClinical characteristicsElderly patientsClinical presentationSpecialty careHospital characteristicsExcess mortalityBaseline differencesMedicine subspecialistsGeneral internists