2024
Racial Differences in 1-Year Mortality after Hospitalization for Chronic Obstructive Pulmonary Disease in the United States.
Jain S, Priya A, Pekow P, Spitzer K, Walkey A, Opara I, Krumholz H, Lindenauer P. Racial Differences in 1-Year Mortality after Hospitalization for Chronic Obstructive Pulmonary Disease in the United States. Annals Of The American Thoracic Society 2024, 21: 585-594. PMID: 37943953, PMCID: PMC10995557, DOI: 10.1513/annalsats.202304-359oc.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseChronic obstructive pulmonary disease hospitalizationsObstructive pulmonary diseaseMedicare beneficiariesWhite racePulmonary diseaseChronic obstructive pulmonary disease exacerbationsChronic obstructive pulmonary disease patientsObstructive pulmonary disease exacerbationsObstructive pulmonary disease patientsHospital-level clusteringPulmonary disease exacerbationsRetrospective cohort studyPulmonary disease patientsCox regression modelIndividual socioeconomic statusDisease exacerbationPulmonary rehabilitationCohort studyDischarge dispositionOverall mortalityIllness severityHospitalized populationCare factorsDisease patients
2021
Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection
McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PLOS ONE 2021, 16: e0243291. PMID: 33788846, PMCID: PMC8011821, DOI: 10.1371/journal.pone.0243291.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionYale New Haven HealthSARS-CoV-2Hospital mortalityRisk of admissionMale sexRisk factorsSARS-CoV-2 testingInvasive mechanical ventilationSevere acute respiratory syndrome virusBurden of diseaseRT-PCR testingAcademic health systemDiverse patient populationsRespiratory syndrome virusEthnic groupsAdult patientsClinical characteristicsDischarge dispositionRespiratory supportPrimary outcomeTreatment guidelinesMechanical ventilationRetrospective studyPatient population
2018
National and Regional Trends in Deep Vein Thrombosis Hospitalization Rates, Discharge Disposition, and Outcomes for Medicare Beneficiaries
Minges KE, Bikdeli B, Wang Y, Attaran RR, Krumholz HM. National and Regional Trends in Deep Vein Thrombosis Hospitalization Rates, Discharge Disposition, and Outcomes for Medicare Beneficiaries. The American Journal Of Medicine 2018, 131: 1200-1208. PMID: 29753792, PMCID: PMC7040884, DOI: 10.1016/j.amjmed.2018.04.033.Peer-Reviewed Original ResearchConceptsDeep vein thrombosisHospitalization ratesVein thrombosisBlack patientsMedicare Standard Analytic FilesProportion of patientsPrincipal discharge diagnosisStandard Analytic FilesSecondary prevention effortsDischarge dispositionHospital lengthInpatient managementReadmission ratesDischarge diagnosisService patientsAdjusted outcomesOutpatient careAnalytic FilesMedicare feeMedicare beneficiariesMortality rateClinical practiceHospitalizationPatientsThrombosis
2014
Trends in left ventricular assist device use and outcomes among Medicare beneficiaries, 2004–2011
Lampropulos JF, Kim N, Wang Y, Desai MM, Barreto-Filho JA, Dodson JA, Dries DL, Mangi AA, Krumholz HM. Trends in left ventricular assist device use and outcomes among Medicare beneficiaries, 2004–2011. Open Heart 2014, 1: e000109. PMID: 25332817, PMCID: PMC4189322, DOI: 10.1136/openhrt-2014-000109.Peer-Reviewed Original ResearchDischarge dispositionLVAD implantationMortality rateRehospitalisation ratesIndex hospitalisationImplantation rateLeft ventricular assist device useVentricular assist device useMedicaid Services paymentsProportion of patientsLong-term outcomesPost-procedure lengthUse of LVADsDevice implantation ratesHospital daysHospitalisation costsHeartMate IILVAD useMedicare feeMedicare populationMedicare beneficiariesService beneficiariesHospitalisationDevice useStay
2010
Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006
Bueno H, Ross JS, Wang Y, Chen J, Vidán MT, Normand SL, Curtis JP, Drye EE, Lichtman JH, Keenan PS, Kosiborod M, Krumholz HM. Trends in Length of Stay and Short-term Outcomes Among Medicare Patients Hospitalized for Heart Failure, 1993-2006. JAMA 2010, 303: 2141-2147. PMID: 20516414, PMCID: PMC3020983, DOI: 10.1001/jama.2010.748.Peer-Reviewed Original ResearchConceptsLength of stayShort-term outcomesHeart failureReadmission ratesHospital mortalityDischarge dispositionRisk ratioThirty-day readmission ratesMortality risk ratioSkilled nursing facilitiesHome care servicesHospital stayOlder patientsUnadjusted analysesMedicare patientsObservational studyMedicare feeNursing facilitiesPatientsStayCare servicesMortalityMarked reductionMean lengthOutcomes
2007
Temporal Trends of Outcomes for Nonagenarians Undergoing Coronary Artery Bypass Grafting, 1993 to 1999
Lichtman JH, Kapoor R, Wang Y, Radford MJ, Allen NB, Krumholz HM. Temporal Trends of Outcomes for Nonagenarians Undergoing Coronary Artery Bypass Grafting, 1993 to 1999. The American Journal Of Cardiology 2007, 100: 1630-1634. PMID: 18036360, DOI: 10.1016/j.amjcard.2007.06.067.Peer-Reviewed Original ResearchConceptsCABG proceduresMortality outcomesMortality rateLong-term mortality outcomesShort-term mortality outcomesOverall crude mortality rateService Medicare patientsCoronary artery bypassLength of stayCrude mortality rateService Medicare beneficiariesSkilled nursing facilitiesHigh mortality rateProjected life expectancyNumber of proceduresArtery bypassDischarge dispositionMedicare patientsMedicare beneficiariesNursing facilitiesNonagenariansMean lengthTemporal trendsLife expectancyWomenChanges in outcomes for internal medicine inpatients after work-hour regulations.
Horwitz LI, Kosiborod M, Lin Z, Krumholz HM. Changes in outcomes for internal medicine inpatients after work-hour regulations. Annals Of Internal Medicine 2007, 147: 97-103. PMID: 17548401, DOI: 10.7326/0003-4819-147-2-200707170-00163.Peer-Reviewed Original ResearchConceptsIntensive care unit utilizationLength of stayDrug-drug interactionsWork-hour regulationsNonteaching servicesHospital deathPharmacist interventionsReadmission ratesConsecutive patientsRetrospective cohort studyInternal medicine patientsInternal medicine inpatientsUnit utilizationAdverse drug-drug interactionsTeaching serviceAcademic medical centerCohort studyDischarge dispositionMedicine inpatientsMedicine patientsFatigue-related errorsMedical CenterRehabilitation facilityRate of dischargePatients