2024
Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy
Khan W, Chopra S, Zheng X, Liu S, Paszkowski P, Valcarce-Aspegren M, Sieu L, Mcgill S, Mccafferty C, Blumenfeld H. Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy. Experimental Neurology 2024, 381: 114925. PMID: 39151596, DOI: 10.1016/j.expneurol.2024.114925.Peer-Reviewed Original ResearchExtracellular single unit recordingsSingle unit recordingsMouse modelNeuronal firingAbsence epilepsyFiring patternsRat modelSeizure initiationMouse model of absence epilepsyIn vivo extracellular single unit recordingNeuronal activityUnit recordingsModel of absence epilepsySomatosensory barrel cortexC3H/HeJ mouse modelNeuronal firing rateHuman absence epilepsyDiverse firing patternsNeuronal rhythmicityArousal stateC3H/HeJ miceBarrel cortexStudy of neuronal activityCortical electroencephalographyFiring rate
2010
Dynamic Time Course of Typical Childhood Absence Seizures: EEG, Behavior, and Functional Magnetic Resonance Imaging
Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H. Dynamic Time Course of Typical Childhood Absence Seizures: EEG, Behavior, and Functional Magnetic Resonance Imaging. Journal Of Neuroscience 2010, 30: 5884-5893. PMID: 20427649, PMCID: PMC2946206, DOI: 10.1523/jneurosci.5101-09.2010.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrainBrain MappingCerebrovascular CirculationChildElectroencephalographyEpilepsy, AbsenceFemaleHumansLinear ModelsMagnetic Resonance ImagingMaleModels, NeurologicalMotor ActivityNeuropsychological TestsPsychomotor PerformanceSeizuresSignal Processing, Computer-AssistedTime FactorsConceptsTypical childhood absence seizuresChildhood absence seizuresAbsence seizuresFMRI decreasesSeizure onsetHz spike-wave dischargesMagnetic resonance imaging changesFunctional magnetic resonance imaging (fMRI) changesTime courseHz generalized spikeSpike-wave dischargesFunctional magnetic resonance imagingMagnetic resonance imagingRepetitive tapping taskLateral parietal cortexLateral frontal cortexImpaired consciousnessPediatric patientsImaging changesEEG time-frequency analysisSeizure endMean durationSeizure initiationGeneralized spikeFMRI changes