2023
Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures
McCafferty C, Gruenbaum B, Tung R, Li J, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu J, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson E, Vitkovskiy P, Sampognaro J, Freedman I, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli B, Herman P, Hyder F, Blumenfeld H. Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures. Nature Communications 2023, 14: 117. PMID: 36627270, PMCID: PMC9832004, DOI: 10.1038/s41467-022-35535-4.Peer-Reviewed Original ResearchConceptsThalamic neuronsAbsence seizuresSeizure onsetNeuronal firingConsciousness-impairing seizuresFemale rat modelLow-frequency electroencephalographic activityFunctional magnetic resonanceBehavioral arrestRat modelRhythmic firingTransient initial peakFiring increasesSeizuresNeuronal mechanismsElectroencephalographic activityNeuronsBrain state changesBrief episodesFiring decreasesInitial peakFiringMagnetic resonanceDistinct patternsOnset
2009
EEG–fMRI in Animal Models
Ellens D, Blumenfeld H. EEG–fMRI in Animal Models. 2009, 485-509. DOI: 10.1007/978-3-540-87919-0_24.Peer-Reviewed Original ResearchCerebral blood flowBrain functionBlood flowCerebral haemodynamic responseElectrical activityBlood flow increasesFundamental neuronal processesCortical electrical activityBrain activityIndividual brain regionsHaemodynamic responseCerebral cortexFunctional imaging technologyCortical neuronsBrain electrical activitySubcortical areasNeuronal activityAnimal modelsNeuronal functionBrain regionsElectrical brain activityNeuronal mechanismsElectrophysiological techniquesEntire brainNeuronal processes