Haidong Lu, PhD
Cards
Research
About
Contact/Administration
Research
About
Contact/Administration
Research
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Titles
Instructor
Appointments
Contact Info
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Titles
Instructor
Appointments
Contact Info
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
Publications Overview
- 33 Publications
- 619 Citations
- 7 Yale Co-Authors
Featured Publication
About
Titles
Instructor
Biography
Haidong Lu is an epidemiologist and methodologist who is passionate about bridging the disciplines of epidemiology/pharmacoepidemiology, statistics, data science, population health, and medical research. His research focuses on leveraging appropriate advanced epidemiologic methods and data science techniques to draw causal inferences from observational data (e.g., electronic health records). Through this approach, he strives to generate accurate and impactful real-world evidence bases that inform health decision-making and promote public health equity. In addition to observational studies, he is dedicated to enhancing methodologies for analyzing randomized controlled trials, particularly in addressing challenges related to non-compliance and generalizability. His substantive research interests center around HIV, substance use, and pharmacoepidemiology. Dr. Lu earned a PhD in Epidemiology with a formal minor in Biostatistics from UNC Gillings School of Global Public Health, and a master's degree from Johns Hopkins Bloomberg School of Public Health. He is also clinically trained with a degree in pharmacy, further reinforcing his diverse and extensive background in health-related fields.
Appointments
General Internal Medicine
InstructorPrimary
Other Departments & Organizations
- General Internal Medicine
- Internal Medicine
- Janeway Society
- Program in Addiction Medicine
Education & Training
- PhD
- The University of North Carolina Gillings School of Global Public Health, Epidemiology (Major)/Biostatistics (Minor)
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0002-7908-2517
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Gregg Gonsalves, PhD
Lauretta Grau, PhD
Benjamin Howell, MD, MPH, MHS
David Fiellin, MD
Forrest W. Crawford, PhD
Robert Heimer, PhD
Publications
Featured Publications
Toward a Clearer Definition of Selection Bias When Estimating Causal Effects
Lu H, Cole S, Howe C, Westreich D. Toward a Clearer Definition of Selection Bias When Estimating Causal Effects. Epidemiology 2022, 33: 699-706. PMID: 35700187, PMCID: PMC9378569, DOI: 10.1097/ede.0000000000001516.Peer-Reviewed Original ResearchCitationsAltmetricMeSH KeywordsRevisiting Overadjustment Bias
Lu H, Cole S, Platt R, Schisterman E. Revisiting Overadjustment Bias. Epidemiology 2021, 32: e22-e23. PMID: 34172691, DOI: 10.1097/ede.0000000000001377.Peer-Reviewed Original ResearchCitationsAltmetricClinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada
Lu H, Cole S, Westreich D, Hudgens M, Adimora A, Althoff K, Silverberg M, Buchacz K, Li J, Edwards J, Rebeiro P, Lima V, Marconi V, Sterling T, Horberg M, Gill M, Kitahata M, Eron J, Moore R. Clinical Effectiveness of Integrase Strand Transfer Inhibitor–Based Antiretroviral Regimens Among Adults With Human Immunodeficiency Virus: A Collaboration of Cohort Studies in the United States and Canada. Clinical Infectious Diseases 2020, 73: e1408-e1414. PMID: 32780095, PMCID: PMC8492356, DOI: 10.1093/cid/ciaa1037.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIntegrase strand transfer inhibitorsHuman immunodeficiency virusHazard ratioEFV groupAntiretroviral therapyStrand transfer inhibitorsClinical outcomesRisk differenceINSTI groupComposite outcomeImmunodeficiency virusClinical effectivenessNorth American AIDS Cohort CollaborationFirst-line antiretroviral therapyEnd-stage liver diseaseLong-term clinical effectivenessEnd-stage renal diseaseLong-term clinical outcomesComposite clinical outcomeFirst ART regimenInitial ART regimensAdverse clinical outcomesModern antiretroviral therapyTransfer inhibitorsAcute myocardial infarctionInflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study
Lu H, Surkan P, Irwin M, Treisman G, Breen E, Sacktor N, Stall R, Wolinsky S, Jacobson L, Abraham A. Inflammation and Risk of Depression in HIV: Prospective Findings From the Multicenter AIDS Cohort Study. American Journal Of Epidemiology 2019, 188: 1994-2003. PMID: 31642472, PMCID: PMC6825834, DOI: 10.1093/aje/kwz190.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHuman immunodeficiency virusMulticenter AIDS Cohort StudyAIDS Cohort StudyInflammatory processCohort studyHigher oddsDepressive symptomsSoluble tumor necrosis factor receptor 2Soluble interleukin-2 receptor αTumor necrosis factor receptor 2B-cell activating factorEpidemiological Studies Depression ScaleInterleukin-2 receptor αNecrosis factor receptor 2Relevant depression symptomsSoluble interleukin-6 receptorPathogenesis of depressionHigh-risk populationRisk of depressionFactor receptor 2Interleukin-6 receptorExploratory factor analysisHIV- menHIV- participantsInflammatory profileGeneralizing the per-protocol treatment effect: The case of ACTG A5095
Lu H, Cole S, Hall H, Schisterman E, Breger T, Edwards J, Westreich D. Generalizing the per-protocol treatment effect: The case of ACTG A5095. Clinical Trials 2018, 16: 52-62. PMID: 30326736, PMCID: PMC6693502, DOI: 10.1177/1740774518806311.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFour-drug antiretroviral regimenThree-drug regimenConventional intentionAntiretroviral regimenVirologic failureTreat comparisonProtocol deviationsRisk differenceTarget populationTreatment assignmentThree-drug armInverse probability weightsACTG A5095Protocol effectUS HIVHazard ratioRandomized trialsInverse oddsTreatment protocolRegimenUS individualsHIVProtocol estimatesTrialsProtocol analysis
2024
The Influence of Perinatal Psychological Changes on Infant Neurodevelopment in Shanghai, China: A Longitudinal Group-based Trajectory Analysis.
Zhang J, Lu H, Sheng Q, Zang E, Zhang Y, Yuan H, Chen B, Tang W. The Influence of Perinatal Psychological Changes on Infant Neurodevelopment in Shanghai, China: A Longitudinal Group-based Trajectory Analysis. J Affect Disord 2024, 361: 291-298. PMID: 38876315, DOI: 10.1016/j.jad.2024.06.029.Peer-Reviewed Original ResearchThe Evolution of Selection Bias in the Recent Epidemiologic Literature—A Selective Overview
Lu H, Howe C, Zivich P, Gonsalves G, Westreich D. The Evolution of Selection Bias in the Recent Epidemiologic Literature—A Selective Overview. American Journal Of Epidemiology 2024, kwae282. PMID: 39136207, DOI: 10.1093/aje/kwae282.Peer-Reviewed Original ResearchCitationsAltmetricSynergistic interaction between pay-it-forward incentives and recreational drug use on hepatitis B virus and hepatitis C virus testing among men who have sex with men in China
Ai W, Xie Y, Lu H, Ai T, Wu D, Zhang Y, Marley G, Ong J, Tucker J, Tang W. Synergistic interaction between pay-it-forward incentives and recreational drug use on hepatitis B virus and hepatitis C virus testing among men who have sex with men in China. Sexually Transmitted Infections 2024, 100: 302-309. PMID: 38862237, PMCID: PMC11283352, DOI: 10.1136/sextrans-2024-056150.Peer-Reviewed Original ResearchAltmetricConceptsHepatitis C virus testingHepatitis C virus testing uptakePay-it-forwardTesting uptakeRecreational drug useStandard-of-care groupIncentive groupPromote hepatitis B virusDrug useHepatitis testingChinese MSMAdditive scaleMSMCommunity connectednessDrug use behaviorsRecreational drugsDonation opportunitiesFree testingParticipantsPooled dataHepatitis B virusHepatitis C virusUse behaviorsMenStudy groupAccessibility of Opioid Treatment Programs Based on Conventional vs Perceived Travel Time Measures
Kim J, Lee J, Thornhill T, Dennett J, Lu H, Howell B, Grau L, Fiellin D, Heimer R, Gonsalves G. Accessibility of Opioid Treatment Programs Based on Conventional vs Perceived Travel Time Measures. JAMA Network Open 2024, 7: e240209. PMID: 38376839, PMCID: PMC10879949, DOI: 10.1001/jamanetworkopen.2024.0209.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsTransit travel timeAccessibility metricsTravel timeTravel componentsAccessibility scoresTransportation burdenTravel burdenOut-of-vehicleComponents of travelConventional accessibility measuresSpatial regression modelsTravel time measurementsPublic transitTransit schedulesAccessibility measuresDeparture timeTravel time analysisTrip durationTravelOperating hoursTime analysisCross-sectional studyOpioid use disorderPolicy recommendationsDecision-makingSpatiotemporal Trends of Birth Defects in North Carolina, 2003-2015
Lu H, Olshan AF, Serre ML, Anthony KM, Fry RC, Forestieri NE, Keil AP. Spatiotemporal Trends of Birth Defects in North Carolina, 2003-2015. American Journal of Epidemiology. 2023. In revision.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
activity Epidemiologic Methods
Journal ServiceAssociate EditorDetails03/05/2024 - Presentactivity Design and Analysis Group (DAG)
Advisory BoardsCo-ChairDetailsThe Veterans Aging Cohort Study (VACS)2024 - Presentactivity Yale Pharmacoepidemiology Workgroup
Advisory BoardsCo-FounderDetailsYale University2024 - Presentactivity AJE Advances: Research in Epidemiology
Journal ServiceAssociate EditorDetails2024 - Presenthonor The Lilienfeld Postdoctoral Prize Paper Award Finalist
National AwardThe Society for Epidemiologic ResearchDetails06/15/2023United States
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