Non-steroidal anti-inflammatory drugs and amyotrophic lateral sclerosis: Results from five prospective cohort studies
Fondell E, O'Reilly ÉJ, Fitzgerald KC, Falcone GJ, McCullough ML, Thun MJ, Park Y, Kolonel LN, Ascherio A. Non-steroidal anti-inflammatory drugs and amyotrophic lateral sclerosis: Results from five prospective cohort studies. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2012, 13: 573-579. PMID: 22871075, PMCID: PMC3474335, DOI: 10.3109/17482968.2012.703209.Peer-Reviewed Original ResearchConceptsNon-steroidal anti-inflammatory drugsProspective cohort studyNSAID useALS riskAnti-inflammatory drugsCohort studyNon-aspirin NSAID useNon-aspirin NSAID usersAmyotrophic lateral sclerosis (ALS) pathologyLarge prospective cohort studyProportional hazards modelAmyotrophic lateral sclerosisCohort-specific estimatesRandom-effects modelAspirin useNSAID usersProspective dataRelative riskPathological studiesLateral sclerosisHazards modelRiskEffects modelDrugsOverall effect