2023
Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism
Mistry P, Garcia-Tsao G. Liver Transplantation for Mahvash Disease, an Inborn Error of Metabolism. New England Journal Of Medicine 2023, 389: 2010-2013. PMID: 37991861, DOI: 10.1056/nejme2310332.Peer-Reviewed Original Research
2021
Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases
Biggins SW, Angeli P, Garcia‐Tsao G, Ginès P, Ling SC, Nadim MK, Wong F, Kim WR. Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology 2021, 74: 1014-1048. PMID: 33942342, DOI: 10.1002/hep.31884.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsVascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases
Northup PG, Garcia‐Pagan J, Garcia‐Tsao G, Intagliata NM, Superina RA, Roberts LN, Lisman T, Valla DC. Vascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases. Hepatology 2021, 73: 366-413. PMID: 33219529, DOI: 10.1002/hep.31646.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2020
SGLT2 inhibitors in patients with cirrhosis and diabetes mellitus: A tertiary center cohort study and insights about a potential therapeutic target for portal hypertension
Saffo S, Garcia‐Tsao G, Taddei T. SGLT2 inhibitors in patients with cirrhosis and diabetes mellitus: A tertiary center cohort study and insights about a potential therapeutic target for portal hypertension. Journal Of Diabetes 2020, 13: 265-269. PMID: 33210815, DOI: 10.1111/1753-0407.13136.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBenzhydryl CompoundsCohort StudiesDiabetes Mellitus, Type 2FemaleGlucosidesGlycated HemoglobinHumansHypertension, PortalLiver CirrhosisMaleMiddle AgedOutcome Assessment, Health CarePolyuriaSodium-Glucose Transporter 2 InhibitorsTertiary Care CentersUrinary Tract InfectionsYoung AdultConceptsSGLT2 inhibitorsPortal hypertensionDiabetes mellitusSodium-glucose cotransporter 2 inhibitorsGlucose cotransporter 2 inhibitorsCenter cohort studyCotransporter 2 inhibitorsCohort of patientsPotential therapeutic targetFavorable pleiotropic effectsCohort studyRenal diseaseClinical trialsClinical dataTherapeutic targetPatientsCirrhosisHypertensionMellitusOngoing evaluationInhibitorsPleiotropic effectsCohortDiseaseTrialsClinical Research in Hepatology in the COVID‐19 Pandemic and Post‐Pandemic Era: Challenges and the Need for Innovation
Verna EC, Serper M, Chu J, Corey K, Fix OK, Hoyt K, Page KA, Loomba R, Li M, Everson GT, Fried MW, Garcia‐Tsao G, Terrault N, Lok AS, Chung RT, Reddy KR. Clinical Research in Hepatology in the COVID‐19 Pandemic and Post‐Pandemic Era: Challenges and the Need for Innovation. Hepatology 2020, 72: 1819-1837. PMID: 32740969, PMCID: PMC7435542, DOI: 10.1002/hep.31491.Peer-Reviewed Original ResearchConceptsClinical researchInvestigational productAcute respiratory syndrome coronavirus 2 pandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemicChronic liver diseaseLong-term followCoronavirus 2 pandemicClinical trial designImplementation of telemedicineHepatitis BLiver diseaseLaboratory monitoringClinical careTrial designCoronavirus disease 2019 (COVID-19) researchNatural historyCompletion of studyTherapeutic developmentNational InstituteCOVID-19 pandemicHepatologyOngoing studiesDiseaseIndustry fundingPandemicAS044 Stage 1b acute kidney injury in cirrhosis is likely due to underlying chronic kidney disease and would be more appropriately re-classified as acute-on-chronic kidney disease
Wong F, Reddy R, Tandon P, O’Leary J, Biggins S, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas H, Subramanian R, Thuluvath P, Kamath P, Thacker L, Bajaj J. AS044 Stage 1b acute kidney injury in cirrhosis is likely due to underlying chronic kidney disease and would be more appropriately re-classified as acute-on-chronic kidney disease. Journal Of Hepatology 2020, 73: s35-s36. DOI: 10.1016/s0168-8278(20)30623-1.Peer-Reviewed Original Research
2018
Esophageal Varices
Jakab S, Garcia-Tsao G. Esophageal Varices. 2018, 195-208. DOI: 10.1007/978-3-319-98506-0_15.Peer-Reviewed Educational MaterialsVariceal hemorrhageEsophageal varicesComplications of cirrhosisEsophageal variceal hemorrhageScreening/surveillanceSecondary prophylaxisVariceal bleedingLiver diseaseTreatment optionsCurrent recommendationsHigh riskCirrhosisPrevention strategiesVaricesComplicationsHemorrhagePatientsProphylaxisBleedingMortalityDiseaseEVHProgressionSeverityCirrhosis and Portal Hypertension: Staging and Prognosis
Garcia-Tsao G. Cirrhosis and Portal Hypertension: Staging and Prognosis. 2018, 1-13. DOI: 10.1007/978-3-319-72628-1_1.Peer-Reviewed Educational MaterialsSignificant portal hypertensionPortal hypertensionDecompensated stagePredominant pathophysiological mechanismPresence of varicesGastroesophageal varicesPrognostic significanceReversible diseasePathophysiological mechanismsDifferent therapiesHypertensionVaricesCirrhosisDecompensationPatientsTherapyDisease
2016
Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases
Garcia‐Tsao G, Abraldes JG, Berzigotti A, Bosch J. Portal hypertensive bleeding in cirrhosis: Risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases. Hepatology 2016, 65: 310-335. PMID: 27786365, DOI: 10.1002/hep.28906.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2008
Portal hypertension and variceal bleeding—Unresolved issues. Summary of an American Association for the study of liver diseases and European Association for the study of the liver single‐topic conference
Garcia‐Tsao G, Bosch J, Groszmann RJ. Portal hypertension and variceal bleeding—Unresolved issues. Summary of an American Association for the study of liver diseases and European Association for the study of the liver single‐topic conference. Hepatology 2008, 47: 1764-1772. PMID: 18435460, DOI: 10.1002/hep.22273.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2003
553 Histologic-hemodynamic correlations in hepatitis C and other chronic liver diseases — is there a histologically mild and severe cirrhosis?
Nagula S, Jain D, Groszmann R, Garcia-Tsao G. 553 Histologic-hemodynamic correlations in hepatitis C and other chronic liver diseases — is there a histologically mild and severe cirrhosis? Hepatology 2003, 38: 426-427. DOI: 10.1016/s0270-9139(03)80595-5.Peer-Reviewed Original Research
1999
The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis
Combes B, Markin R, Wheeler D, Rubin R, West A, Mills A, Eigenbrodt E, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Carithers R. The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis. Hepatology 1999, 30: 602-605. PMID: 10462363, PMCID: PMC3935822, DOI: 10.1002/hep.510300315.Peer-Reviewed Original ResearchConceptsFlorid duct lesionsPrimary biliary cirrhosisBile duct destructionDuct lesionsUrsodeoxycholic acidDuct destructionBiliary cirrhosisPlacebo-controlled trialNeedle biopsy specimensUDCA patientsAdvanced diseasePlacebo medicationEarly diseaseBiopsy specimensPatientsLesionsBeneficial effectsPathology literaturePrevalenceCirrhosisPlaceboMedicationsDiseaseYearsHepatopathologist
1998
Portal hypertension
Garcia-Tsao G. Portal hypertension. Current Opinion In Gastroenterology 1998, 14: 256-264. DOI: 10.1097/00001574-199805000-00012.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsComplications of cirrhosisPortal hypertensionHepatic insufficiencySpontaneous bacterial peritonitisInsufficiency contributesVariceal hemorrhageCirrhotic patientsBacterial peritonitisLive diseaseHypertensionMajor syndromesCirrhosisComplicationsInsufficiencyVaricesPeritonitisAscitesHemorrhagePatientsSyndromeDisease
1991
Partial hepatectomy for Caroli's syndrome. Report of two patients with long-term follow-up.
Orozco H, Takahashi T, Garcia-Tsao G, Mercado M, Quiroz F, Hernandez-Cendejas A. Partial hepatectomy for Caroli's syndrome. Report of two patients with long-term follow-up. Hepatogastroenterology 1991, 38: 33-5. PMID: 2026386.Peer-Reviewed Original ResearchConceptsCaroli syndromePartial hepatectomyBiliary tract surgeryAbdominal CT scanBest current treatmentIntrahepatic bile ductsPercutaneous cholangiographyPersistent feverSurgical drainageAbdominal abscessBile ductClinical evidenceCystic dilatationRare entityTherapeutic choiceCurrent treatmentCT scanPrevious historyPatientsSyndromeHepatectomyDiseaseCholangiographyAbscessSurgery
1990
Surgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein.
Orozco-Zepeda H, Takahashi T, Angel Mercado M, García-Tsao G, Hernández-Ortiz J. Surgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein. Revista De Gastroenterología De México 1990, 55: 215-9. PMID: 2091189.Peer-Reviewed Original ResearchConceptsHemorrhagic portal hypertensionSugiura procedurePortal hypertensionAssociated liver diseasePortal vein thrombosisProtein C deficiencyActuarial survivalOperative deathsSurgical treatmentVein thrombosisEsophageal varicesLiver diseaseMean ageSurgical stagePortal veinC deficiencyPatientsHypertensionThrombosisEPVTVaricesHemorrhageCasesYearsDisease
1989
Hepatic fibropolycystic disease in Mexico. Study of 82 cases.
Torres-Barrera G, García-Tsao G, Quiroz F, Ferrari. Hepatic fibropolycystic disease in Mexico. Study of 82 cases. Revista De Investigación Clínica 1989, 41: 45-52. PMID: 2727432.Peer-Reviewed Original ResearchConceptsCongenital hepatic fibrosisFibropolycystic diseaseLiver function testsPolycystic liver diseaseHepatic fibrosisCholedochal cystCaroli's diseaseLiver diseaseFunction testsMean agePolycystic kidneysInstituto Nacional de la NutriciónRenal insufficiencyVariceal hemorrhageSalvador ZubiránPolycystic diseaseIsolated diseaseIndividual patientsLarge seriesFibrosisCholangitisDiseasePatientsCystsKidney
1988
Deficiency of protein C in patients with portal vein thrombosis
Orozco H, Guraieb E, Takahashi T, Garcia‐Tsao G, Hurtado R, Anaya R, Ruiz‐Arguelles G, Hernandez‐Ortiz J, Casillas M, Guevara L. Deficiency of protein C in patients with portal vein thrombosis. Hepatology 1988, 8: 1110-1111. PMID: 3262079, DOI: 10.1002/hep.1840080522.Peer-Reviewed Original ResearchConceptsPortal vein thrombosisVein thrombosisThromboembolic diseaseProtein C deficiencyPortal hypertensionC deficiencyProtein CMesenteric venous thrombosisSystemic thromboembolic diseaseUpper gastrointestinal bleedingTime of surgeryGastroesophageal varicesGastrointestinal bleedingIntestinal resectionVenous thrombosisLiver biopsySugiura procedureRecurrent episodesThrombosisPatientsDiseaseHypertensionVaricesSurgeryDeficiency