Demonstration of naturalistic methods for cocaine smoking by human volunteers
Foltin R, Fischman M, Nestadt G, Stromberger H, Cornell E, Pearlson G. Demonstration of naturalistic methods for cocaine smoking by human volunteers. Drug And Alcohol Dependence 1990, 26: 145-154. PMID: 2242715, DOI: 10.1016/0376-8716(90)90121-t.Peer-Reviewed Original ResearchConceptsVenous blood levelsClinical research unitBlood level curvesFirst doseSubsequent dosesBlood pressureDosing sessionsBlood levelsAcute toleranceCocaine smokingHeart rateDose sessionAscending limbBaseline levelsCardiovascular activityHuman volunteersSubjective effectsTransient increaseResearch volunteersDosesMale research volunteersCocaineVolunteersSubjectsLimb