2023
Altered Resting-State Activity and Connectivity in Late-Life Depression with Suicidal Ideation
Wang L, Manning K, Pearlson G, Steffens D. Altered Resting-State Activity and Connectivity in Late-Life Depression with Suicidal Ideation. American Journal Of Geriatric Psychiatry 2023, 31: e22-e23. DOI: 10.1016/j.jagp.2023.02.031.Peer-Reviewed Original ResearchDefault mode networkVentrolateral prefrontal cortexLate-life depressionFunctional connectivityPrefrontal cortexOlder adultsOlder depressed adultsBrain activityDepressed adultsSuicidal ideationGreater brain activityVisual cortexWeaker functional connectivityStronger functional connectivityResting-state fMRI dataResting-state activitySuicidal behaviorWhole-brain voxelwiseNon-SI groupROI functional connectivityDepression severitySI groupCerebellar cortexCerebellar functional connectivityResting activity
2022
Acute cannabis-related alterations in an fMRI time estimation task
Patel K, Stevens M, Adhikari S, Book G, Mubeen M, Pearlson G. Acute cannabis-related alterations in an fMRI time estimation task. 2022 DOI: 10.26828/cannabis.2022.02.000.26.Peer-Reviewed Original ResearchMedial temporal cortexPosterior cingulate cortexSomatosensory motor cortexPremotor cortexMotor cortexTemporal cortexMedial prefrontal cortexCingulate cortexFrontal cortexLong-duration stimuliAnterior cingulateInferior frontal cortexVisual cortexBrain activation differencesMultiple comparison correctionPlacebo conditionActivation differencesDuration stimuliPrefrontal cortexVisual areasOccipital junctionDose-related mannerMid-cingulate cortexSignificant activation differencesPopular recreational drug
2020
Neuroanatomical Sex Differences in the Visual Cortex of Individuals With Psychosis: Findings From the Bipolar-Schizophrenia Network on Intermediate Phenotypes
Turkozer H, Lizano P, Adhan I, Ivleva E, Lutz O, Zeng A, Raymond N, Clementz B, Pearlson G, Sweeney J, Gershon E, Keshavan M, Tamminga C. Neuroanatomical Sex Differences in the Visual Cortex of Individuals With Psychosis: Findings From the Bipolar-Schizophrenia Network on Intermediate Phenotypes. Biological Psychiatry 2020, 87: s205. DOI: 10.1016/j.biopsych.2020.02.533.Peer-Reviewed Original Research
2012
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Weiner M, Aisen P, Petersen R, Jack C, Jagust W, Trojanowki J, Toga A, Beckett L, Green R, Saykin A, Morris J, Liu E, Montine T, Gamst A, Thomas R, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe R, Foster N, Reiman E, Chen K, Mathis C, Cairns N, Taylor-Reinwald L, Trojanowki J, Shaw L, Lee V, Korecka M, Crawford K, Neu S, Foroud T, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder P, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider L, Pawluczyk S, Spann B, Brewer J, Vanderswag H, Heidebrink J, Lord J, Johnson K, Doody R, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig L, Bell K, Morris J, Ances B, Carroll M, Leon S, Mintun M, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah R, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon M, Glodzik L, De Santi S, Doraiswamy P, Petrella J, Coleman R, Arnold S, Karlawish J, Wolk D, Smith C, Jicha G, Hardy P, Lopez O, Oakley M, Simpson D, Porsteinsson A, Goldstein B, Martin K, Makino K, Ismail M, Brand C, Mulnard R, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey A, Lah J, Cellar J, Burns J, Anderson H, Swerdlow R, Apostolova L, Lu P, Bartzokis G, Silverman D, Graff-Radford N, Parfitt F, Johnson H, Farlow M, Hake A, Matthews B, Herring S, van Dyck C, Carson R, MacAvoy M, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Ging-Yuek, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam M, Lipowski K, Wu C, Johnson N, Sadowsky C, Martinez W, Villena T, Turner R, Johnson K, Reynolds B, Sperling R, Johnson K, Marshall G, Frey M, Yesavage J, Taylor J, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson A, Norbash A, Johnson P, Obisesan T, Wolday S, Bwayo S, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee T, Bartha R, Johnson S, Asthana S, Carlsson C, Potkin S, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre D, Kataki M, Zimmerman E, Celmins D, Brown A, Pearlson G, Blank K, Anderson K, Santulli R, Schwartz E, Sink K, Williamson J, Garg P, Watkins F, Ott B, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen H, Miller B, Mintzer J, Longmire C, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 3985-3990. PMID: 22343285, PMCID: PMC3309762, DOI: 10.1073/pnas.1105829109.Peer-Reviewed Original ResearchConceptsGenome-wide significant associationWide association studyCommon genetic variationCommon genetic variantsGenes genomeGenomic regionsProportional surface areasAssociated SNPsGenetic variationGenetic mechanismsAssociation studiesStrong linkage disequilibriumLinkage disequilibriumGenetic variantsSNPsNormal cortical architectureEnvironmental factorsRemainder of cortexCortical surface areaVisual cortexTwo- toGenomeHomologUTRGenes
1999
(Non)stationarity of temporal dynamics in fMRI
Calhoun V, Adali T, Pearlson G. (Non)stationarity of temporal dynamics in fMRI. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society 1999, 2: 1079 vol.2. DOI: 10.1109/iembs.1999.804239.Peer-Reviewed Original ResearchPrimary visual cortexFunctional MRIHemodynamic responseVisual cortexBrain regionsObserved hemodynamic responsesBlood supplyHigher cognitive functionsCognitive functionLatency shiftNeuronal patternsCortexAuthors' initial resultsCurrent studyFMRI experimentMean waveformOverall changeInitial resultsMRI
1998
Visualizing spatially distributed hemodynamic lag times in event-related functional MRI: estimation of a characteristic visual "impulse response"
Calhoun V, Adali T, Kraut M, Rivkin P, Pearlson G. Visualizing spatially distributed hemodynamic lag times in event-related functional MRI: estimation of a characteristic visual "impulse response". Annual International Conference Of The IEEE Engineering In Medicine And Biology Society 1998, 4: 2124-2127 vol.4. DOI: 10.1109/iembs.1998.747028.Peer-Reviewed Original Research