2023
Altered Resting-State Activity and Connectivity in Late-Life Depression with Suicidal Ideation
Wang L, Manning K, Pearlson G, Steffens D. Altered Resting-State Activity and Connectivity in Late-Life Depression with Suicidal Ideation. American Journal Of Geriatric Psychiatry 2023, 31: e22-e23. DOI: 10.1016/j.jagp.2023.02.031.Peer-Reviewed Original ResearchDefault mode networkVentrolateral prefrontal cortexLate-life depressionFunctional connectivityPrefrontal cortexOlder adultsOlder depressed adultsBrain activityDepressed adultsSuicidal ideationGreater brain activityVisual cortexWeaker functional connectivityStronger functional connectivityResting-state fMRI dataResting-state activitySuicidal behaviorWhole-brain voxelwiseNon-SI groupROI functional connectivityDepression severitySI groupCerebellar cortexCerebellar functional connectivityResting activity
2017
92. Peripheral Oxytocin and Vasopressin Modulates Regional Brain Activity Differently in Men and Women With Schizophrenia
Rubin L, Li S, Yao L, Keedy S, Reilly J, Hill S, Bishop J, Carter S, Pournajafi-Nazarloo H, Drogos L, Gershon E, Pearlson G, Tamminga C, Clementz B, Keshavan M, Lui S, Sweeney J. 92. Peripheral Oxytocin and Vasopressin Modulates Regional Brain Activity Differently in Men and Women With Schizophrenia. Schizophrenia Bulletin 2017, 43: s50-s50. PMCID: PMC5475587, DOI: 10.1093/schbul/sbx021.131.Peer-Reviewed Original ResearchHigher AVP levelsHigher ALFFMale patientsCerebellar cortexFrontal cortexArginine vasopressinHigher OT levelsPosterior cingulateOT levelsFemale patientsLower ALFFAVP levelsPoor verbal fluencyHealthy individualsRegional cerebral functionSpontaneous neuronal activitySex-dependent mannerAVP serum concentrationsBrain activityRegional brain activityVerbal fluencyEmotion processingSuperior temporal gyrusClinical associationsSerum concentrations