2011
P2‐035: Preliminary evaluation of the amyloid PET Radioligand [18F]MK‐3328 in Alzheimer's Disease patients
Sanabria‐Bohorquez S, Hostetler E, Van Laere K, Koole M, Bormans G, Serdons K, de Hoon J, Vandenberghe R, Versijpt J, De Lepeleire I, Reynders T, Tamagnan G, Marek K, Seibyl J, Jennings D, Barret O, Koren A, Rosen L, Hargreaves R, Evelhoch J, Sur C, Forman M. P2‐035: Preliminary evaluation of the amyloid PET Radioligand [18F]MK‐3328 in Alzheimer's Disease patients. Alzheimer's & Dementia 2011, 7: s319-s319. DOI: 10.1016/j.jalz.2011.05.925.Peer-Reviewed Original Research
2008
6‐[123I]Iodo‐2‐[[4‐(2‐methoxyphenyl) piperazin‐1‐yl]methyl]imidazo[1,2‐a]pyridine as potential SPECT agent for imaging dopamine D4 receptor: synthesis and in vivo evaluation in a nonhuman primate
Alagille D, Koren A, Kudej G, Staley J, Cosgrove K, Seibyl J, Tamagnan G. 6‐[123I]Iodo‐2‐[[4‐(2‐methoxyphenyl) piperazin‐1‐yl]methyl]imidazo[1,2‐a]pyridine as potential SPECT agent for imaging dopamine D4 receptor: synthesis and in vivo evaluation in a nonhuman primate. Journal Of Labelled Compounds And Radiopharmaceuticals 2008, 51: 202-206. DOI: 10.1002/jlcr.1500.Peer-Reviewed Original Research
2000
5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors
Mukhin A, Gündisch D, Horti A, Koren A, Tamagnan G, Kimes A, Chambers J, Vaupel D, King S, Picciotto M, Innis R, London E. 5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors. Molecular Pharmacology 2000, 57: 642-649. PMID: 10692507, DOI: 10.1124/mol.57.3.642.Peer-Reviewed Original ResearchConceptsNicotinic acetylcholine receptorsAlpha4beta2 nAChRsAcetylcholine receptorsNeuronal nicotinic acetylcholine receptorsAffinity of epibatidineRat adrenal glandMuscle-type nAChRsSubtype-selective ligandsAlpha4beta2 subtypeAdrenal glandRat brainSelective radioligandBrain regionsNAChRsBeta4 subunitsRadioiodinated ligandBeta2 subunitVivo studiesEpibatidineVivo experimentsHuman brainSubtypesRadioligandBrainReceptors