Simultaneous Insulinlike Growth Factor I and Insulin Resistance in Obese Zucker Rats
Jacob R, Sherwin R, Greenawalt K, Shulman G. Simultaneous Insulinlike Growth Factor I and Insulin Resistance in Obese Zucker Rats. Diabetes 1992, 41: 691-697. PMID: 1587396, DOI: 10.2337/diab.41.6.691.Peer-Reviewed Original ResearchConceptsInsulinlike growth factor IGrowth factor IObese Zucker ratsObese ratsLean ratsZucker ratsChain amino acid concentrationsFactor IGlucose uptakeIGF-I infusionDiabetic BB ratsIGF-I levelsEffects of IGFEuglycemic insulin clampLean control ratsObese groupBB ratsInsulin clampInsulin resistanceLean controlsControl ratsRats 6Amino acid concentrationsVivo effectsIGF