2014
Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging
Petibon Y, Huang C, Ouyang J, Reese T, Li Q, Syrkina A, Chen Y, Fakhri G. Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging. Medical Physics 2014, 41: 042503. PMID: 24694156, PMCID: PMC3971824, DOI: 10.1118/1.4868458.Peer-Reviewed Original ResearchConceptsPoint spread function modelRespiratory motionPoint spread functionPET-MR scannersPencil-beam navigator echoesPET-MRMeasurement of respiratory motionPSF modelRespiratory motion correctionDetector blur effectsModel respiratory motionLung-liver interfacePatient studiesLesion contrastSimultaneous PET-MRSource of image degradationWhole-body PET imagingPET reconstruction algorithmMoving lesionsPhantom experiment resultsPET eventsContrast recoveryNavigator echoesIterative reconstruction processMotion correction
2011
Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study
Surti S, Scheuermann J, Fakhri G, Daube-Witherspoon M, Lim R, Abi-Hatem N, Moussallem E, Benard F, Mankoff D, Karp J. Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study. Journal Of Nuclear Medicine 2011, 52: 712-719. PMID: 21498523, PMCID: PMC3104282, DOI: 10.2967/jnumed.110.086678.Peer-Reviewed Original ResearchConceptsLocalization receiver operating characteristicsTime-of-flight PETLong scan timesArea under the LROC curveScan timeFunction of scan timePatient sizeTime-of-flight (TOFLROC curveLow-uptake lesionsTOF imagesTOF kernelLesion detection taskTOF-PETWhole-body oncologyLesion detection performanceScanner fieldPhantom studyPatient body mass indexProbability of correct localizationLesion detectionSphere dataBody mass indexLarger patientsReceiver operating characteristic