2021
Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas
Marin T, Zhuo Y, Lahoud R, Tian F, Ma X, Xing F, Moteabbed M, Liu X, Grogg K, Shusharina N, Woo J, Lim R, Ma C, Chen Y, El Fakhri G. Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas. Radiotherapy And Oncology 2021, 167: 269-276. PMID: 34808228, PMCID: PMC8934266, DOI: 10.1016/j.radonc.2021.09.034.Peer-Reviewed Original ResearchConceptsGross tumor volumeRadiation therapy treatment planningGross tumor volume contoursGross tumor volume delineationTherapy treatment planningIntra-observer variabilityConsensus contoursGTV contoursPre-operative CT imagesSoft tissue sarcomasRadiation oncologistsTumor volumeBone sarcomasTreatment planningAccurate contoursCT imagesDelineation procedureSarcomaSoft tissueConfidence levelRadiationPatientsHausdorff distanceMultiple contoursX-ray
2017
Guest Editorial Low-Dose CT: What Has Been Done, and What Challenges Remain?
Liang J, La Riviere P, Fakhri G, Glick S, Siewerdsen J. Guest Editorial Low-Dose CT: What Has Been Done, and What Challenges Remain? IEEE Transactions On Medical Imaging 2017, 36: 2409-2416. DOI: 10.1109/tmi.2017.2768978.Peer-Reviewed Original ResearchCone-beam CTMulti-detector row CTDiscovery of X-raysIntroduction of computed tomographyMonitoring of therapeutic responseMulti-detector-rowImage-guided interventionsProjection dataMagnetic resonance imagingPositron emission tomographyTherapeutic responseEmergency examinationTreatment planningVolumetric imagesDiagnostic imagingEmission tomographyImaging modalitiesResonance imagingX-rayMedical imaging modalitiesCTTomographyTomographic imagesPositron
2015
Mapping 15O Production Rate for Proton Therapy Verification
Grogg K, Alpert N, Zhu X, Min C, Testa M, Winey B, Normandin M, Shih H, Paganetti H, Bortfeld T, Fakhri G. Mapping 15O Production Rate for Proton Therapy Verification. International Journal Of Radiation Oncology • Biology • Physics 2015, 92: 453-459. PMID: 25817530, PMCID: PMC4431894, DOI: 10.1016/j.ijrobp.2015.01.023.Peer-Reviewed Original ResearchConceptsDecay constantProton treatment planningMonte Carlo predictionsProton therapyPhantom materialTreatment deliveryPhantomThigh activityPositron emission tomographyProduction rateDynamic PET measurementsTreatment planningRabbit thigh muscleClearance rateProtonIsotopesChanges due to therapyRadionuclide speciesOxygen-15ConstantDecayImaging targetsMontePositronEffects of perfusion
2004
A general-spectral method for improved quantitative SPECT imaging of indium-111
Moore S, Park M, Fakhri G, Gerbaudo V, Zimmerman R. A general-spectral method for improved quantitative SPECT imaging of indium-111. 2004, 6: 3682-3684. DOI: 10.1109/nssmic.2004.1466680.Peer-Reviewed Original ResearchRadiotherapy treatment planningList-mode dataFree of scatterQuantitative SPECT imagingScatter compensation methodsList-mode acquisitionDown-scatterScattered photonsPhoton scatteringPhotopeakQuantitative SPECTOSEM reconstructionSPECT imagesLeastsquares procedureDose specificationAttenuation projectionNoisy projectionsScatteringTreatment planningSphere activitySphere locationIndium-111PhotonsContrast valuesSphere position