2017
Joint reconstruction of Ictal/inter‐ictal SPECT data for improved epileptic foci localization
Rakvongthai Y, Fahey F, Borvorntanajanya K, Tepmongkol S, Vutrapongwatana U, Zukotynski K, Fakhri G, Ouyang J. Joint reconstruction of Ictal/inter‐ictal SPECT data for improved epileptic foci localization. Medical Physics 2017, 44: 1437-1444. PMID: 28211105, PMCID: PMC5462456, DOI: 10.1002/mp.12167.Peer-Reviewed Original ResearchConceptsSPECT reconstruction methodDifferential imagingLow-noise datasetConventional subtraction methodLesion contrastSPECT projection dataEpileptic focus localizationHoffman phantomPatient studiesReconstruction methodJoint methodSPECT projectionsHead phantomPhantom locationsSubtraction methodPhantom studyNuclear medicine physiciansAttenuation backgroundPhantomConventional subtraction approachFocus localizationConventional subtractionReceiver operating characteristicLow noiseProjection data
2011
Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study
Surti S, Scheuermann J, Fakhri G, Daube-Witherspoon M, Lim R, Abi-Hatem N, Moussallem E, Benard F, Mankoff D, Karp J. Impact of Time-of-Flight PET on Whole-Body Oncologic Studies: A Human Observer Lesion Detection and Localization Study. Journal Of Nuclear Medicine 2011, 52: 712-719. PMID: 21498523, PMCID: PMC3104282, DOI: 10.2967/jnumed.110.086678.Peer-Reviewed Original ResearchConceptsLocalization receiver operating characteristicsTime-of-flight PETLong scan timesArea under the LROC curveScan timeFunction of scan timePatient sizeTime-of-flight (TOFLROC curveLow-uptake lesionsTOF imagesTOF kernelLesion detection taskTOF-PETWhole-body oncologyLesion detection performanceScanner fieldPhantom studyPatient body mass indexProbability of correct localizationLesion detectionSphere dataBody mass indexLarger patientsReceiver operating characteristic