2016
Validation of Bayesian analysis of compartmental kinetic models in medical imaging
Sitek A, Li Q, Fakhri G, Alpert N. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Physica Medica 2016, 32: 1252-1258. PMID: 27692754, PMCID: PMC5720163, DOI: 10.1016/j.ejmp.2016.09.010.Peer-Reviewed Original ResearchConceptsAccurate estimation of uncertaintyComputer simulationsMedical imagesPosterior distributionDistributed noiseTime series of imagesClosed-formSeries of imagesData setsKinetic parametersMarkov chain Monte Carlo methodsPosterior distributions of kinetic parametersNon-linear least squares methodAccurate estimationComputerLeast-squares methodKinetic modelEstimation of kinetic parametersF18-fluorodeoxyglucoseBayesian estimationImagesStatistical inferenceMonte Carlo methodEstimates of uncertaintyInformation
2005
Fast Monte Carlo Estimation of Patient and Detector Scatter and Crosstalk Contamination in SPECT Imaging
Ouyang J, Moore S, Park M, Fakhri G. Fast Monte Carlo Estimation of Patient and Detector Scatter and Crosstalk Contamination in SPECT Imaging. 2005, 3: 1560-1562. DOI: 10.1109/nssmic.2005.1596616.Peer-Reviewed Original ResearchDetector effectsEnergy windowTriple-energy window methodConvolution-based forced detectionPhoton interaction pointSimulate photon interactionsLower energy windowScattering mapCompton scatteringPhoton contributionEnergy binsPhoton interactionsMultiple photonsDetector scatterImaging isotopesCoherent scatteringAttenuation phantomMonte Carlo methodPhotoelectric effectInteraction pointPhantom experimentsDetectorCrosstalk contaminationScatteringCarlo method