2019
Renal clearable nanochelators for iron overload therapy
Kang H, Han M, Xue J, Baek Y, Chang J, Hu S, Nam H, Jo M, El Fakhri G, Hutchens M, Choi H, Kim J. Renal clearable nanochelators for iron overload therapy. Nature Communications 2019, 10: 5134. PMID: 31723130, PMCID: PMC6853917, DOI: 10.1038/s41467-019-13143-z.Peer-Reviewed Original ResearchConceptsIron overloadIntravenous injectionDaily sc injectionsUrinary iron excretionSecondary iron overloadIron-overloaded miceAdverse side effectsIron chelatorsIron overload disordersGastrointestinal bleedingSC injectionIron excretionLiver fibrosisSide effectsKidney damageKidney failureIron overload therapyIron levelsToxic ironPharmacokinetic propertiesDeferoxamineNanochelatorKidneyExcretionInjection
2016
Endocrine-specific NIR fluorophores for adrenal gland targeting
Ashitate Y, Levitz A, Park M, Hyun H, Venugopal V, Park G, Fakhri G, Henary M, Gioux S, Frangioni J, Choi H. Endocrine-specific NIR fluorophores for adrenal gland targeting. Chemical Communications 2016, 52: 10305-10308. PMID: 27476533, PMCID: PMC4982771, DOI: 10.1039/c6cc03845j.Peer-Reviewed Original Research