2018
Real‐Time Imaging of Brain Tumor for Image‐Guided Surgery
Hu S, Kang H, Baek Y, Fakhri G, Kuang A, Choi H. Real‐Time Imaging of Brain Tumor for Image‐Guided Surgery. Advanced Healthcare Materials 2018, 7: e1800066. PMID: 29719137, PMCID: PMC6105507, DOI: 10.1002/adhm.201800066.Peer-Reviewed Original ResearchConceptsNormal tissuesBrain tumorsCompleteness of surgical resectionDifferentiate cancerous lesionsIncomplete tumor resectionReal-time image guidanceRemoval of normal tissueDecrease surgical complicationsOptical fluorescence imagingMalignant brain tumorsBrain tumor treatmentIntraoperative guidance techniquesImage-guided surgeryMagnetic resonance imagingResidual tumorResection marginsSurgical resectionPrognostic factorsTumor resectionOncologic surgeonsSurgical complicationsResection completenessImage guidanceImage-guidedAdjacent normal tissues
2016
Tissue-Specific Near-Infrared Fluorescence Imaging
Owens E, Henary M, Fakhri G, Choi H. Tissue-Specific Near-Infrared Fluorescence Imaging. Accounts Of Chemical Research 2016, 49: 1731-1740. PMID: 27564418, PMCID: PMC5776714, DOI: 10.1021/acs.accounts.6b00239.Peer-Reviewed Original ResearchConceptsSingle-photon emission computed tomographyPositron emission tomographyVital tissuesReal-time intraoperative navigationReal-time image guidanceContrast agentsTargeted NIR fluorophoresEmission computed tomographyTissue-specific contrast agentsEffective imaging agentsTissue-specific targetingReal-time delineationIntraoperative successTargeted therapyImage guidanceTumor tissuesEPR effectIntraoperative navigationSurgical fieldClinical imaging technologyDiagnostic utilityClinical useEmission tomographySurgical spaceTarget tissues