2022
Simulation study of a 50 ps panel TOF PET imager
Pestotnik R, Razdevšek G, Dolenec R, Fakhri G, Križan P, Majewski S, Studen A, Korpar S. Simulation study of a 50 ps panel TOF PET imager. Journal Of Instrumentation 2022, 17: c12010. DOI: 10.1088/1748-0221/17/12/c12010.Peer-Reviewed Original ResearchPET scannerGamma detectorGamma raysTime-of-flight positron emission tomographyState-of-the-art clinical PET scannersGamma detection efficiencyClinical PET scannerImaging large objectsImproved time resolutionArtifact-free imagesDifferent phantomsDetector arrangementTime-of-flightBiograph VisionImage quality parametersDetection efficiencyTiming accuracyTime resolutionDetectorFWHMPositron emission tomographyReconstructed imagesRaysPositron emission tomography imagingMultichannel system
2015
A Sub-MM Spatial Resolution LYSO: CE Detector for Small Animal PET
Sabet H, Bläckberg L, Ozsahin D, Sitek A, El-Fakhri G. A Sub-MM Spatial Resolution LYSO: CE Detector for Small Animal PET. 2015, 1-4. DOI: 10.1109/nssmic.2015.7582201.Peer-Reviewed Original ResearchLaser induced optical barriersOptical barrierLYSO:Ce crystalsIncident gamma raysLYSO:CeInter-pixel gapPixelated scintillatorLYSO crystalsPET detectorsPixelated crystalsCe crystalsGamma raysSub-mmMechanical pixelationLYSOCE detectorSimulation codeBarrier sizeAnimal PETHigh-spatial resolutionScintillationSmall-animal PETDetectorLaser energy densityEnergy density
2014
Novel Cost-Effective and High-Performance Modular Detectors for Emission Tomography Systems
Sabet H, El-Fakhri G. Novel Cost-Effective and High-Performance Modular Detectors for Emission Tomography Systems. 2014, 1-3. DOI: 10.1109/nssmic.2014.7430755.Peer-Reviewed Original ResearchLaser induced optical barriersScintillation light spreadIncident gamma raysInter-pixel gapEmission tomography systemSpatial resolutionScintillator arrayGamma raysOptical barrierMechanical pixelationAnimal PETCE arrayLow packing fractionScintillationSmall-animal PETTomography systemSPECT imagesCross-sectionPixel separationArray fabricationLYSOPacking fractionRaysResolutionProcess yield
2013
Dual-Tracer PET Using Generalized Factor Analysis of Dynamic Sequences
El Fakhri G, Trott C, Sitek A, Bonab A, Alpert N. Dual-Tracer PET Using Generalized Factor Analysis of Dynamic Sequences. Molecular Imaging And Biology 2013, 15: 666-674. PMID: 23636489, PMCID: PMC3812387, DOI: 10.1007/s11307-013-0631-1.Peer-Reviewed Original ResearchConceptsEmit gamma raysPositron emission tomographyNear-simultaneous imagingSingle-photon emissionBrain PET studiesGamma raysSingle-photon emission computed tomographyActivity distributionRaclopride studiesEmission computed tomographyPositron emission tomography radiopharmaceuticalsSimultaneous imagingD2 bindingFactor analysis of dynamic sequencesActivity estimationTime activity curvesRacloprideFDGRhesus monkeysEmission tomographyPET studiesActivation curveBrain metabolismEmissionSimulate human data
2009
Monte Carlo modeling of cascade gamma rays in 86Y PET imaging: preliminary results
Zhu X, Fakhri G. Monte Carlo modeling of cascade gamma rays in 86Y PET imaging: preliminary results. Physics In Medicine And Biology 2009, 54: 4181-4193. PMID: 19521011, PMCID: PMC3111055, DOI: 10.1088/0031-9155/54/13/014.Peer-Reviewed Original ResearchConceptsCascade gamma raysScatter fractionGamma raysPhoton energy distributionLow count ratesHigh-energy photonsMonte Carlo programScatter correction methodGATE simulation packageMonte Carlo modelDevelopment of correction methodsSpatial resolutionGamma photonsEnergy windowCount rateScattering eventsRandom coincidencesEnergy distributionPhantom acquisitionsPersonal dosimetryPET imagingVariance reduction techniquesPhotonsCorrection methodSimSET
2006
Monte Carlo Modeling of Cascade Gamma Rays in PET
Zhu X, Fakhri G. Monte Carlo Modeling of Cascade Gamma Rays in PET. 2011 IEEE Nuclear Science Symposium Conference Record 2006, 6: 3522-3525. DOI: 10.1109/nssmic.2006.353759.Peer-Reviewed Original ResearchCascade gamma raysGamma raysGamma-ray emitting isotopesDetector dead timeMonte Carlo modelPET imagingGamma eventsScatter fractionQuantitative PET imagingTorso phantomSingles ratesMonte Carlo simulationsDecrease of intensityHigh-activity regionsPhantom experimentsReconstructed volumePhantomRaysCarlo simulationsDead timeDetectorReconstructed imagesCascade typeImage intensityMonte