Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI
Liu Y, Hanley T, Chen H, Long S, Gambhir S, Cheng Z, Wu J, Fakhri G, Anvari B, Zaman R. Non-Invasive Photoacoustic Imaging of In Vivo Mice with Erythrocyte Derived Optical Nanoparticles to Detect CAD/MI. Scientific Reports 2020, 10: 5983. PMID: 32249814, PMCID: PMC7136251, DOI: 10.1038/s41598-020-62868-1.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseMyocardial-infarctionTail vein 1 hourIndocyanine greenWeeks old male C57BL/6 miceLeft anterior descending (LADAnterior descending (LADMale C57BL/6 miceAtherosclerotic lesionsCoronary artery ligationTen-week-old male C57BL/6 miceAtherosclerotic plaquesC57BL/6 miceNon-invasiveArtery ligationInflammatory cellsPortal tractsArtery diseaseFluorescence in vivo imagingParenchymal necrosisCoronary arteryClinical detectionPathological changesContrast agentsLesions