2020
Dynamic Cardiac SPECT for diagnostic and theranostics applications: latest results
Bläckberg L, Sajedi S, Anderson O, Feng Y, Fakhri G, Furenlid L, Sabet H. Dynamic Cardiac SPECT for diagnostic and theranostics applications: latest results. 2020, 00: 1-3. DOI: 10.1109/nss/mic42677.2020.9508002.Peer-Reviewed Original ResearchCsI:Tl crystalsMPPC arraysTl crystalsCsI:Tl scintillatorGamma-ray energiesCardiac SPECTCsI:TlLow energy resolutionCardiac SPECT imagingGamma cameraConventional gamma cameraResolution recovery techniquesSensL SiPMsEnergy resolutionStopping powerTl scintillatorDetector modulesReadout electronicsDynamic cardiac SPECTPinhole collimatorHigh power lasersPhantom studyCollimatorDetectorSiPM
2019
Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard
Pan T, Einstein S, Kappadath S, Grogg K, Gomez C, Alessio A, Hunter W, Fakhri G, Kinahan P, Mawlawi O. Performance evaluation of the 5‐Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2‐2012 Standard. Medical Physics 2019, 46: 3025-3033. PMID: 31069816, PMCID: PMC7251507, DOI: 10.1002/mp.13576.Peer-Reviewed Original ResearchConceptsAxial field-of-viewPeak noise-equivalent count rateNoise-equivalent count rateField of viewCount ratePET performanceNational Electrical Manufacturers Association NU-2Transaxial field of viewPET/CT systemTime resolutionMean energy resolutionConventional photomultiplier tubesCount rate performanceImage quality phantomSpatial resolution measurementsFiltered back projection algorithmImage qualityEnergy resolutionAcquisition timeNU 2Count lossDetector designPhotomultiplier tubeMean energyPET/MR systems
2017
Simulation study of light transport in laser-processed LYSO:Ce detectors with single-side readout
Bläckberg L, Fakhri G, Sabet H. Simulation study of light transport in laser-processed LYSO:Ce detectors with single-side readout. Physics In Medicine And Biology 2017, 62: 8419-8440. PMID: 29047453, PMCID: PMC5736368, DOI: 10.1088/1361-6560/aa8dea.Peer-Reviewed Original ResearchConceptsDetector typesLYSO:Ce detectorsLYSO:Ce crystalsBarrier refractive indexScintillation light transportImproved energy resolutionRefractive indexLaser-processed crystalsCollection efficiencyLight transportPixel-like patternScintillation lightMPPC arraysEnergy resolutionPixel arrayDOI informationPulsed laser beamLight response functionLine profilesCe crystalsMonolithic crystalsBarrier patternsCrystal bulkTime resolutionCE detector
2016
Novel laser‐processed CsI:Tl detector for SPECT
Sabet H, Bläckberg L, Uzun-Ozsahin D, El-Fakhri G. Novel laser‐processed CsI:Tl detector for SPECT. Medical Physics 2016, 43: 2630-2638. PMID: 27147372, PMCID: PMC5148208, DOI: 10.1118/1.4947294.Peer-Reviewed Original ResearchConceptsOptical barrierPeak-to-valley (P/VCsI:Tl crystalsCrystal bulkMultipixel photon counterPixel-like patternScintillation lightEnergy resolutionKeV gammasPixelated scintillatorScintillator samplesPhoton counterTL detectorsTl crystalsFabricated detectorScintillationCrystal thicknessSpatial resolutionPixel arrayDetectorBarrier patternsFabricated arraysCSICrystalBulk
2010
Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections
Guérin B, Fakhri G. Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections. IEEE Transactions On Medical Imaging 2010, 30: 759-773. PMID: 21118770, PMCID: PMC3120772, DOI: 10.1109/tmi.2010.2095025.Peer-Reviewed Original ResearchConceptsScattered coincidencesEnergy resolutionE-pdfNCAT phantomDependent correctionsEnergy of individual photonsScatter correctionEnergy dependent correctionsEnergy probability density functionScatter correction schemeTotal energy spectrumList-mode acquisitionEnergy informationPositron emission tomography dataActivity distribution estimationScatter sinogramIndividual photonsEnergy spectrumCylindrical phantomEnergy distributionMonte Carlo simulationsScattering approachPhotonsScatteringScattering component
2008
Sequential and simultaneous dual‐isotope brain SPECT: Comparison with PET for estimation and discrimination tasks in early Parkinson disease
Trott C, Fakhri G. Sequential and simultaneous dual‐isotope brain SPECT: Comparison with PET for estimation and discrimination tasks in early Parkinson disease. Medical Physics 2008, 35: 3343-3353. PMID: 18697558, PMCID: PMC2673561, DOI: 10.1118/1.2940605.Peer-Reviewed Original ResearchConceptsEnergy resolutionTime-of-flight PET scannerRealistic Monte Carlo simulationsAcquisition energy windowSequential SPECTSystem energy resolutionGamma cameraEnergy windowThree-head cameraPET scannerEmission energyMonte Carlo simulationsDual-isotope SPECTSimultaneous SPECTBrain PETTwo-headed cameraCarlo simulationsProdromal disease stagesIdentical physiological conditionsSpatial resolutionDiscrimination taskStriatal sizeActivity concentrationsEarly identification of PDCamera head