2016
Localizing Sources of Brain Disease Progression with Network Diffusion Model
Hu C, Hua X, Ying J, Thompson P, Fakhri G, Li Q. Localizing Sources of Brain Disease Progression with Network Diffusion Model. IEEE Journal Of Selected Topics In Signal Processing 2016, 10: 1214-1225. PMID: 28503250, PMCID: PMC5423678, DOI: 10.1109/jstsp.2016.2601695.Peer-Reviewed Original ResearchMild cognitive impairmentEfficient gradient descent methodGradient descent methodAlzheimer's Disease Neuroimaging InitiativeBrain connectivity networksDescent methodOrigin of dementiaDementia sourcesOrigin of Alzheimer's diseaseAlzheimer's diseaseEffective treatment of neurodegenerative diseasesDementiaMagnetic resonance imagingBrain atrophy patternsProgression of brain atrophyCognitive impairmentInverse problemNetworkSource of dementiaConnectivity networksTreatment of neurodegenerative diseasesAtrophy patterns
2014
Inferring Sources of Dementia Progression with Network Diffusion Model
Hu C, Hua X, Thompson P, El Fakhri G, Li Q. Inferring Sources of Dementia Progression with Network Diffusion Model. Lecture Notes In Computer Science 2014, 8679: 42-49. DOI: 10.1007/978-3-319-10581-9_6.Peer-Reviewed Original Research
2004
Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease.
El Fakhri G, Kijewski M, Albert M, Johnson K, Moore S. Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease. Journal Of Nuclear Medicine 2004, 45: 2026-31. PMID: 15585477.Peer-Reviewed Original ResearchConceptsProdromal Alzheimer's diseaseMemory problemsAlzheimer's diseaseDiagnosis of prodromal Alzheimer's diseaseDiagnosis of prodromal ADClinical tasksMRI volume estimationsVariable collimator responseFollow-up periodDementiaGeneral spectral methodConverter groupFollow-upProdromal ADUniform attenuation mapQuestion groupsPairwise discriminant analysisSubjectsQuantitative approachDiscrimination accuracyAnterior cingulate gyrusAttenuation mapNonuniform attenuation mapNormal groupCingulate gyrus