2019
Quantification of PET Myocardial Blood Flow
Pelletier-Galarneau M, Martineau P, El Fakhri G. Quantification of PET Myocardial Blood Flow. Current Cardiology Reports 2019, 21: 11. PMID: 30815744, DOI: 10.1007/s11886-019-1096-x.Peer-Reviewed Original ResearchConceptsPositron emission tomographyMyocardial blood flowMyocardial flow reserveMicrovascular dysfunctionEvaluation of cardiac allograft vasculopathyAssessment of coronary microvascular dysfunctionFlow reserveHyperemic myocardial blood flowFlow quantificationCardiac allograft vasculopathyMarkers of disease severityCoronary microvascular dysfunctionImprove risk stratificationQuantification of myocardial blood flowFractional flow reserveMyocardial blood flow quantificationAllograft vasculopathyPrognostic valueRisk stratificationEpicardial diseaseAcademic centersReviewThe aimClinical aspectsEmission tomographyBlood flow
2017
Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz
Guehl N, Normandin M, Wooten D, Rozen G, Sitek A, Ruskin J, Shoup T, Ptaszek L, El Fakhri G, Alpert N. Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz. European Journal Of Nuclear Medicine And Molecular Imaging 2017, 44: 1538-1546. PMID: 28365789, DOI: 10.1007/s00259-017-3684-6.Peer-Reviewed Original ResearchConceptsMyocardial blood flowMicrosphere flow measurementsBlood flowStress myocardial blood flowSingle-scan protocolClinical applicationShort-axis viewMyocardial blood flow measurementsPET dataBlood flow changesIntroduction of adenosineHalf-life of 18FAdenosine infusionRadiotracer injectionAxis viewMyocardial segmentsHealthy pigsClinical translationPET acquisitionTwo-injectionPig modelIschemic areaPorcine modelHalf-lifeAdenosine
2012
Single‐scan rest/stress imaging 18F‐labeled flow tracers
Alpert N, Fang Y, Fakhri G. Single‐scan rest/stress imaging 18F‐labeled flow tracers. Medical Physics 2012, 39: 6609-6620. PMID: 23127055, PMCID: PMC3482258, DOI: 10.1118/1.4754585.Peer-Reviewed Original Research
2010
WE‐D‐201B‐03: Recent Advances in PET Quantitation of Myocardial Blood Flow
Fakhri G. WE‐D‐201B‐03: Recent Advances in PET Quantitation of Myocardial Blood Flow. Medical Physics 2010, 37: 3433-3433. DOI: 10.1118/1.3469414.Peer-Reviewed Original Research