2013
Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, Fakhri G. Feasibility of Using Distal Endpoints for In-Room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3290-3297. DOI: 10.1109/tns.2013.2278140.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyIn-roomMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesRadiological decayBeamDistal endpointsProtonNative nucleiFeasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy
Grogg K, Zhu X, Min C, Winey B, Bortfeld T, Paganetti H, Shih H, El Fakhri G. Feasibility of using distal endpoints for In-room PET Range Verification of Proton Therapy. IEEE Transactions On Nuclear Science 2013, 60: 3890-3894. PMID: 24464031, PMCID: PMC3900284, DOI: 10.1109/nssmic.2012.6551892.Peer-Reviewed Original ResearchPET distributionsNuclear reactionsProton therapyMC-PETSimulated positron emission tomographyMonte CarloPET resolutionPositron emission tomographyRange verificationBiological washoutDose depthThreshold energyDose deliveryCross sectionPlanned doseMC simulationsIndividual beamsSimPETOne-dimensional profilesIn-roomRadiological decayBeamDistal endpointsProtonNative nucleiClinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy
Min C, Zhu X, Winey B, Grogg K, Testa M, Fakhri G, Bortfeld T, Paganetti H, Shih H. Clinical Application of In-Room Positron Emission Tomography for In Vivo Treatment Monitoring in Proton Radiation Therapy. International Journal Of Radiation Oncology • Biology • Physics 2013, 86: 183-189. PMID: 23391817, PMCID: PMC3640852, DOI: 10.1016/j.ijrobp.2012.12.010.Peer-Reviewed Original ResearchConceptsIn-room positron emission tomographyProton therapyIn-roomPositron emission tomography scanIn-room PET scannerPassive scattering proton therapyShapes of target volumesPositron emission tomographyMC predictionBeam range uncertaintiesMeasured PET imagesMonte CarloProton radiation therapyLocal elemental compositionBiological washoutScan timeTreatment headTreatment verificationRange uncertaintiesTarget volumePET scan timePET scannerPET systemComputed tomographyMC results
2011
Monitoring proton radiation therapy with in-room PET imaging
Zhu X, España S, Daartz J, Liebsch N, Ouyang J, Paganetti H, Bortfeld T, Fakhri G. Monitoring proton radiation therapy with in-room PET imaging. Physics In Medicine And Biology 2011, 56: 4041-4057. PMID: 21677366, PMCID: PMC3141290, DOI: 10.1088/0031-9155/56/13/019.Peer-Reviewed Original ResearchConceptsIn-room positron emission tomographyIn-roomProton therapy treatment roomPositron emission tomography systemProton range verificationSoft tissue-equivalent materialMonte Carlo predictionsTissue-equivalent materialsPositron emission tomography acquisition timesProton radiation therapyPositron emission tomographyBiological washoutRange verificationProton therapyList-modeActivity distribution patternsPhantom studyTreatment roomPET acquisitionSoft tissue regionsIn vivo verificationDeep-siteOff-line modalityPositron emission tomography dataAdenoid cystic carcinoma
2010
SU‐GG‐J‐149: Feasibility of In‐Room PET Imaging for in Vivo Proton Beam Range Verification
España S, Zhu X, Daartz J, Liebsch N, Fakhri G, Bortfeld T, Paganetti H. SU‐GG‐J‐149: Feasibility of In‐Room PET Imaging for in Vivo Proton Beam Range Verification. Medical Physics 2010, 37: 3180-3180. DOI: 10.1118/1.3468372.Peer-Reviewed Original ResearchRange verificationIn-roomProton therapyIn vivo range verificationProton beam range verificationPassive scattering proton therapyBeam range verificationIn-room measurementsOff-line protocolsFalloff positionsBiological washoutTreatment couchCount ratePET imagingTreatment positionPET scannerAttenuation correctionTreatment roomPET scansCo-registration accuracyCT numbersCalculated uncertaintiesPatient studiesWashout modelTreatment planning
2009
SU‐FF‐J‐129: In‐Room Proton Range Verification Using Mobile NeuroPET ‐ Feasibility Study
Knopf A, Zhu X, Parodi K, Paganetti H, Bortfeld T, Fakhri G. SU‐FF‐J‐129: In‐Room Proton Range Verification Using Mobile NeuroPET ‐ Feasibility Study. Medical Physics 2009, 36: 2506-2506. DOI: 10.1118/1.3181421.Peer-Reviewed Original ResearchProton range verificationRange verificationPET/CT scannerCommercial PET/CT scannersWater equivalent rangePositron emission tomographyBiological washoutPMMA phantomProton fieldsProton beamActivity depth profilesProton treatmentPhantom studyTreatment roomIn-roomPositron emission tomography scanPositron emission tomography dataPatient repositioningPhantomPositron emission tomography imagingProtonDepth profilesPET/CT imagingRadiation treatmentTotal dose