2016
Validation of Bayesian analysis of compartmental kinetic models in medical imaging
Sitek A, Li Q, Fakhri G, Alpert N. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Physica Medica 2016, 32: 1252-1258. PMID: 27692754, PMCID: PMC5720163, DOI: 10.1016/j.ejmp.2016.09.010.Peer-Reviewed Original ResearchConceptsAccurate estimation of uncertaintyComputer simulationsMedical imagesPosterior distributionDistributed noiseTime series of imagesClosed-formSeries of imagesData setsKinetic parametersMarkov chain Monte Carlo methodsPosterior distributions of kinetic parametersNon-linear least squares methodAccurate estimationComputerLeast-squares methodKinetic modelEstimation of kinetic parametersF18-fluorodeoxyglucoseBayesian estimationImagesStatistical inferenceMonte Carlo methodEstimates of uncertaintyInformation
2012
Parametric imaging with Bayesian priors: A validation study with 11C-Altropane PET
Fang Y, Fakhri G, Becker J, Alpert N. Parametric imaging with Bayesian priors: A validation study with 11C-Altropane PET. NeuroImage 2012, 61: 131-138. PMID: 22425668, DOI: 10.1016/j.neuroimage.2012.03.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlgorithmsBayes TheoremBiasCarbon RadioisotopesCocaineData Interpretation, StatisticalFemaleHumansImage Processing, Computer-AssistedKineticsLeast-Squares AnalysisMaleMiddle AgedNeuroimagingNonlinear DynamicsNormal DistributionPopulationPositron-Emission TomographyRadiopharmaceuticalsReference ValuesSample SizeYoung Adult