2023
Biomechanical and transcriptional evidence that smooth muscle cell death drives an osteochondrogenic phenotype and severe proximal vascular disease in progeria
Murtada S, Kawamura Y, Cavinato C, Wang M, Ramachandra A, Spronck B, Li D, Tellides G, Humphrey J. Biomechanical and transcriptional evidence that smooth muscle cell death drives an osteochondrogenic phenotype and severe proximal vascular disease in progeria. Biomechanics And Modeling In Mechanobiology 2023, 22: 1333-1347. PMID: 37149823, PMCID: PMC10544720, DOI: 10.1007/s10237-023-01722-5.Peer-Reviewed Original ResearchConceptsPulse wave velocitySmooth muscle cell deathMuscle cell deathDisease processOsteochondrogenic phenotypeAdverse extracellular matrix remodelingImportant cardiovascular implicationsProgressive aortic diseaseProximal elastic arteriesVentricular diastolic dysfunctionProgressive disease processSmooth muscle cellsCell deathCardiovascular sequelaeDiastolic dysfunctionCardiovascular implicationsExtracellular matrix remodelingAortic diseasePrimary diagnosisVascular diseaseAccumulation of proteoglycansMuscular arteriesAortic structureAortic wallLate calcification
1998
Pathogenesis of Systemic Air Embolism During Bronchoscopic Nd:YAG Laser Operations
Tellides G, Ugurlu B, Kim R, Hammond G. Pathogenesis of Systemic Air Embolism During Bronchoscopic Nd:YAG Laser Operations. The Annals Of Thoracic Surgery 1998, 65: 930-934. PMID: 9564904, DOI: 10.1016/s0003-4975(98)00109-x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAirAluminum SilicatesAortic DiseasesBronchial NeoplasmsBronchoscopyEchocardiography, TransesophagealElectrocardiographyEmbolism, AirEndoscopyEquipment DesignFemaleHeart DiseasesHumansHypotensionIntracranial Embolism and ThrombosisLaser TherapyLung NeoplasmsMaleMiddle AgedMonitoring, IntraoperativeMyocardial IschemiaNeodymiumSafetyUltrasonography, InterventionalYttriumConceptsSystemic air embolismAir embolismSystemic air emboliIschemic electrocardiographic changesLaser tumor ablationNeurologic complicationsCatastrophic complicationThird patientElectrocardiographic changesTransesophageal echocardiographyAir emboliEmbolismTumor ablationComplicationsPatientsSafety recommendationsBronchoscopic NdLaser fiberHypotensionEchocardiographyEmboliEmbolicPathogenesis