2023
Recruited macrophages elicit atrial fibrillation
Hulsmans M, Schloss M, Lee I, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous F, Keller D, Bening C, Green U, Lennerz J, Mitchell R, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong C, Pierson R, Aster J, Rohde D, Wojtkiewicz G, Weissleder R, Swirski F, Tellides G, Tolis G, Melnitchouk S, Milan D, Ellinor P, Naxerova K, Nahrendorf M. Recruited macrophages elicit atrial fibrillation. Science 2023, 381: 231-239. PMID: 37440641, PMCID: PMC10448807, DOI: 10.1126/science.abq3061.Peer-Reviewed Original ResearchConceptsAtrial fibrillationStromal cellsMitral valve regurgitationHeart failureValve regurgitationInflammatory monocytesMacrophage expansionMonocyte migrationMouse atriaFibrillationHuman atriumAtriumCell-cell interaction analysisSingle-cell transcriptomesMiceCell compositionHypertensionTranscriptome changesImmunotherapySPP1CellsRegurgitationObesityPatientsArrhythmias
2014
A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms
Di Achille P, Tellides G, Figueroa C, Humphrey J. A haemodynamic predictor of intraluminal thrombus formation in abdominal aortic aneurysms. Proceedings Of The Royal Society A 2014, 470: 20140163. DOI: 10.1098/rspa.2014.0163.Peer-Reviewed Original ResearchAbdominal aortic aneurysmIntraluminal thrombusAortic aneurysmThrombus formationUseful clinical predictorIntraluminal thrombus formationOscillatory shear indexClinical predictorsBlood-borne particlesHaemodynamic predictorsAbdominal aortaCarotid arteryHealthy subjectsThin thrombusClinical utilityHaemodynamic featuresComplex haemodynamicsThrombusTreatment planningComplex biomechanicsPatientsAneurysmsEndothelial mechanobiologyReliable predictorLesions
2000
Effect of left ventricular volume on results of coronary artery bypass grafting
Kim R, Ugurlu B, Tereb D, Wackers F, Tellides G, Elefteriades J. Effect of left ventricular volume on results of coronary artery bypass grafting. The American Journal Of Cardiology 2000, 86: 1261-1264. PMID: 11090805, DOI: 10.1016/s0002-9149(00)01216-9.Peer-Reviewed Original ResearchConceptsCoronary artery bypassArtery bypassSignificant left ventricular dilationLeft ventricular dilationLV chamber sizeLV ejection fractionMedium-term survivalSurgical revascularizationAngina symptomsEjection fractionIschemic cardiomyopathyLV dilationVentricular dilationVentricular sizeVentricular volumePatientsSignificant reductionBypassChamber sizeDilationRevascularizationCardiomyopathySymptomsCoronary artery bypass for advanced left ventricular dysfunction
Elefteriades J, Tellides G, Samady H, Yepremyan M, Darr U, Wackers F, Zaret B. Coronary artery bypass for advanced left ventricular dysfunction. Developments In Cardiovascular Medicine 2000, 225: 15-31. DOI: 10.1007/978-0-585-29191-8_2.Peer-Reviewed Original ResearchAdvanced left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery bypassVentricular dysfunctionArtery bypassSuch patientsCoronary artery bypass surgeryArtery bypass surgeryLarge multicenter trialsOpen heart surgeryCoronary revascularizationBypass surgeryMulticenter trialHeart surgeryRisk of operationPatientsDysfunctionBypassInexorable deteriorationCABGSurgeryLongevity benefitsScientific evaluationRevascularizationCardiologists
1998
Pathogenesis of Systemic Air Embolism During Bronchoscopic Nd:YAG Laser Operations
Tellides G, Ugurlu B, Kim R, Hammond G. Pathogenesis of Systemic Air Embolism During Bronchoscopic Nd:YAG Laser Operations. The Annals Of Thoracic Surgery 1998, 65: 930-934. PMID: 9564904, DOI: 10.1016/s0003-4975(98)00109-x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAirAluminum SilicatesAortic DiseasesBronchial NeoplasmsBronchoscopyEchocardiography, TransesophagealElectrocardiographyEmbolism, AirEndoscopyEquipment DesignFemaleHeart DiseasesHumansHypotensionIntracranial Embolism and ThrombosisLaser TherapyLung NeoplasmsMaleMiddle AgedMonitoring, IntraoperativeMyocardial IschemiaNeodymiumSafetyUltrasonography, InterventionalYttriumConceptsSystemic air embolismAir embolismSystemic air emboliIschemic electrocardiographic changesLaser tumor ablationNeurologic complicationsCatastrophic complicationThird patientElectrocardiographic changesTransesophageal echocardiographyAir emboliEmbolismTumor ablationComplicationsPatientsSafety recommendationsBronchoscopic NdLaser fiberHypotensionEchocardiographyEmboliEmbolicPathogenesis
1994
Retrosternal ileocolic esophageal replacement in children revisited Antireflux role of the ileocecal valve
Touloukian R, Tellides G. Retrosternal ileocolic esophageal replacement in children revisited Antireflux role of the ileocecal valve. Journal Of Thoracic And Cardiovascular Surgery 1994, 107: 1067-1072. PMID: 8159028, DOI: 10.1016/s0022-5223(94)70382-5.Peer-Reviewed Original ResearchConceptsIleocecal valveEsophageal replacementEsophageal atresiaGastric tube interpositionSymptomatic gastroesophageal refluxPostoperative respiratory complicationsMonths of ageIleocolic interpositionOperative deathsGastroesophageal refluxPulmonary aspirationRespiratory complicationsAnastomotic leakPostoperative refluxPrimary anastomosisBarium swallowPediatric patientsGastrostomy tubeRegular dietPatientsRefluxAtresiaStrictureColonInterposition