2021
Adherence to Guidelines for the Administration of Intraoperative Antibiotics in a Nationwide US Sample
Bardia A, Treggiari MM, Michel G, Dai F, Tickoo M, Wai M, Schuster K, Mathis M, Shah N, Kheterpal S, Schonberger RB. Adherence to Guidelines for the Administration of Intraoperative Antibiotics in a Nationwide US Sample. JAMA Network Open 2021, 4: e2137296. PMID: 34905007, PMCID: PMC8672234, DOI: 10.1001/jamanetworkopen.2021.37296.Peer-Reviewed Original ResearchConceptsSurgical site infectionAntibiotic prophylaxis guidelinesWeight-adjusted dosingInfectious Diseases SocietyAntibiotic choiceProphylaxis guidelinesCohort studyDiseases SocietyOverall adherenceFuture quality improvement effortsStudy periodAntibiotic administration guidelinesPrimary end pointTiming of administrationGynecological surgical proceduresQuality improvement effortsIntraoperative antibioticsOverall nonadherenceNoncardiac surgeryAdult patientsEmergency surgeryFirst doseGuideline adherenceSurgical encountersAmerica guidelinesVariation in propofol induction doses administered to surgical patients over age 65
Schonberger RB, Bardia A, Dai F, Michel G, Yanez D, Curtis JP, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N. Variation in propofol induction doses administered to surgical patients over age 65. Journal Of The American Geriatrics Society 2021, 69: 2195-2209. PMID: 33788251, PMCID: PMC8373684, DOI: 10.1111/jgs.17139.Peer-Reviewed Original ResearchConceptsPropofol induction dosesInduction dosesEndotracheal intubationGeneral anesthetic inductionPropofol induction dosePercent of patientsRetrospective observational studyLarge multicenter cohortSurgical patientsMulticenter cohortPropofol doseBolus doseGeneral anesthesiaInduction dosePropofol inductionPresent studyAnesthetic inductionDose administrationAdvanced agePatient variablesObservational studyProvider practicesAnaesthetic practiceClinical consequencesDosing decisions
2020
Prevalence of aberrant blood pressure readings across two automated intraoperative blood pressure monitoring systems among patients undergoing caesarean delivery.
Schonberger RB, Gonzalez-Fiol A, Fardelmann KL, Bardia A, Michel G, Dai F, Banack T, Alian A. Prevalence of aberrant blood pressure readings across two automated intraoperative blood pressure monitoring systems among patients undergoing caesarean delivery. Blood Pressure Monitoring 2020, 26: 78-83. PMID: 33234814, PMCID: PMC8715608, DOI: 10.1097/mbp.0000000000000495.Peer-Reviewed Original ResearchConceptsBlood pressure readingsCaesarean deliveryBP readingsMultivariable logistic regression analysisPressure readingsCesarean delivery patientsComparable patient cohortsIntraoperative blood pressureRetrospective observational studySame surgical procedurePre-specified covariatesLogistic regression analysisBlood pressureDelivery patientsSimilar patientsPatient cohortSurgical centersBP measurementsBP monitoring systemObservational studyBP monitorInclusion criteriaSurgical proceduresRelative oddsPatientsAn Analysis of Anesthesia Induction Dosing in Female Older Adults
Chen EY, Michel G, Zhou B, Dai F, Akhtar S, Schonberger RB. An Analysis of Anesthesia Induction Dosing in Female Older Adults. Drugs & Aging 2020, 37: 435-446. PMID: 32300966, PMCID: PMC7359723, DOI: 10.1007/s40266-020-00760-3.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPostinduction hypotensionGeneral anesthesiaPresent cohortPostoperative acute kidney injuryLarge tertiary teaching hospitalOlder adultsFrailty of patientsGynecologic oncology surgeryImmediate hemodynamic effectsPropofol induction dosesPercentage of patientsRetrospective observational studyTertiary teaching hospitalPerioperative vital signsHigher propofol dosesFemale older adultsAKI associationInotrope administrationKidney injurySurgical populationHemodynamic effectsDose adjustmentPrimary outcomeFemale patients
2019
Preference Phenotypes in Support of Shared Decision–Making at Point‐of‐Care for Patients With Rheumatoid Arthritis: A Proof‐of‐Concept Study
Hsiao B, Binder‐Finnema P, Nowell W, Michel G, Wiedmeyer C, Fraenkel L. Preference Phenotypes in Support of Shared Decision–Making at Point‐of‐Care for Patients With Rheumatoid Arthritis: A Proof‐of‐Concept Study. Arthritis Care & Research 2019, 71: 629-637. PMID: 29953733, PMCID: PMC6310675, DOI: 10.1002/acr.23684.Peer-Reviewed Original ResearchConceptsDisease-modifying antirheumatic drugsNew disease-modifying antirheumatic drugsValues clarification toolPost-test visitsMore disease-modifying antirheumatic drugsTest visitsPretest/post-test studyAntirheumatic drugsMore patientsOutpatient visitsRheumatoid arthritisConcept studyPost-test studyPatientsPatient valuesSD lengthPost-test phaseVisitsActive RAVisit timeCarePretest phaseEscalation decisionsPreference phenotypesPhenotypeImpact of Information Presentation Format on Preference for Total Knee Replacement Surgery
Fraenkel L, Nowell WB, Stake CE, Venkatachalam S, Eyler R, Michel G, Peters E. Impact of Information Presentation Format on Preference for Total Knee Replacement Surgery. Arthritis Care & Research 2019, 71: 379-384. PMID: 29799668, PMCID: PMC6252282, DOI: 10.1002/acr.23605.Peer-Reviewed Original Research
2017
Preference phenotypes to facilitate shared decision-making in rheumatoid arthritis
Fraenkel L, Nowell WB, Michel G, Wiedmeyer C. Preference phenotypes to facilitate shared decision-making in rheumatoid arthritis. Annals Of The Rheumatic Diseases 2017, 77: 678. PMID: 29247126, PMCID: PMC5898982, DOI: 10.1136/annrheumdis-2017-212407.Peer-Reviewed Original ResearchConceptsBothersome side effectsRare side effectRheumatoid arthritisSide effectsSerious infectionsOnset of actionJanus kinase inhibitorPreferences of patientsMethotrexate monotherapyTriple therapyParenteral medicationsPoint of careTreatment preferencesGroup 2Patient valuesPatientsGroup 4Target strategyGroup 5Kinase inhibitorsConjoint analysis surveyLatent class analysisLarge groupArthritisMedications