Solubilization and partial purification of the thiazide diuretic receptor from rabbit renal cortex
Ellison D, Morrisey J, Desir G. Solubilization and partial purification of the thiazide diuretic receptor from rabbit renal cortex. Biochimica Et Biophysica Acta 1991, 1069: 241-249. PMID: 1932064, DOI: 10.1016/0005-2736(91)90131-q.Peer-Reviewed Original ResearchConceptsHigh-affinity receptorRenal cortexCortical homogenatesDistal tubulesHigh-performance liquid chromatographyDistal tubule fragmentsRenal cortical microsomesRenal distal tubulesThiazide diuretic receptorRenal cortical membranesExclusion high performance liquid chromatographyRat renal cortexRenal cortical homogenatesCortical microsomesRabbit renal cortexReceptor densityCortical membranesSize-exclusion high-performance liquid chromatographyRabbit receptorThiazide receptorCl- transport pathwaysPercoll gradient centrifugationDiuretic drugsTubule fragmentsReceptors