1996
Genomic structure and regulation of Kcn1, a cGMP-gated potassium channel
Yao X, Liu Y, Tung F, Desir GV. Genomic structure and regulation of Kcn1, a cGMP-gated potassium channel. American Journal Of Physiology 1996, 271: f37-f41. PMID: 8760241, DOI: 10.1152/ajprenal.1996.271.1.f37.Peer-Reviewed Original ResearchConceptsCis-regulatory elementsPromoter regionEnhancer elementsNovel potassium channel geneMajor transcription initiation siteTypical TATA boxTranscription initiation sitePhorbol esterPotassium channel genesLuciferase reporter constructsPotassium channelsGenomic structurePorcine kidney cell lineDeletion analysisRabbit geneTATA boxAcid proteinGene transcriptionKidney cell lineReporter constructsChannel genesSequence analysisPrimer extensionInitiation siteNorthern blot
1995
Molecular characterization of voltage and cyclic nucleotide-gated potassium channels in kidney
Desir G. Molecular characterization of voltage and cyclic nucleotide-gated potassium channels in kidney. Kidney International 1995, 48: 1031-1035. PMID: 8569064, DOI: 10.1038/ki.1995.386.Peer-Reviewed Original ResearchConceptsRenal K channelsMolecular characterizationInitial molecular characterizationPotassium channelsMammalian cellsMembrane proteinsMolecular biologyCell membraneK channelsDiverse groupPhysiologic roleKinetic propertiesPotential physiologic rolePassive movementBiologyProteinPhysiologyKidneyMembraneCharacterizationCellsExtensive data