2009
Regulation of blood pressure and cardiovascular function by renalase
Desir GV. Regulation of blood pressure and cardiovascular function by renalase. Kidney International 2009, 76: 366-370. PMID: 19471322, DOI: 10.1038/ki.2009.169.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseGlomerular filtration rateBlood pressureKidney diseasePlasma catecholaminesCardiovascular functionKnockout miceEnd-stage kidney diseaseRenalase knockout mouseSingle nucleotide polymorphismsRenalase levelsCardiovascular riskEssential hypertensionFiltration rateCardiac functionCardiac ischemiaRenalase geneSignificant fallAnimal modelsRenalaseCatecholaminesHypertensionPatientsFold stimulationAbnormalities
2008
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease
Desir GV. Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease. Current Opinion In Nephrology & Hypertension 2008, 17: 181-185. PMID: 18277152, DOI: 10.1097/mnh.0b013e3282f521ba.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseKidney diseaseBlood pressureAnimal modelsCardiac functionEnd-stage renal diseaseRegulation of renalaseSalt-dependent hypertensionDevelopment of hypertensionSystolic blood pressurePlasma renalaseRenalase deficiencyCatecholamine administrationSympathetic toneRenal diseaseKidney functionSubtotal nephrectomyPlasma catecholaminesCardiovascular diseaseHypertensionLower plasmaRenalaseCatecholaminesDiseaseAbnormalities