1997
Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Effect of left ventricular function on the assessment of myocardial viability by technectium-99m sestamibi and correlation with positron emission tomography in patients with healed myocardial infarcts or stable angina pectoris, or both. The American Journal Of Cardiology 1997, 80: 1007-1013. PMID: 9352969, DOI: 10.1016/s0002-9149(97)00594-8.Peer-Reviewed Original ResearchConceptsCoronary artery diseasePositron emission tomographyLV dysfunctionArtery diseaseGroup 2Myocardial viabilityGroup 1Ejection fractionModerate coronary artery diseaseEmission tomographyModerate LV dysfunctionSevere LV dysfunctionStable angina pectorisLV ejection fractionGlobal LV dysfunctionAccuracy of technetiumSingle photon emissionSemiquantitative SPECTVentricular dysfunctionViability detectionAngina pectorisVentricular functionReduced perfusionSestamibi SPECTMyocardial infarct
1996
Resting Tc-99m sestamibi SPECT underestimates myocardial viability in patients with severe ischemic left ventricular dysfunction: Comparison with ammonia/FDG PET
Arrighi J, Ng C, Dey H, Wackers F, Soufer R. Resting Tc-99m sestamibi SPECT underestimates myocardial viability in patients with severe ischemic left ventricular dysfunction: Comparison with ammonia/FDG PET. Journal Of The American College Of Cardiology 1996, 27: 162. DOI: 10.1016/s0735-1097(96)80876-x.Peer-Reviewed Original Research
1995
Mental stress induced left ventricular dysfunction: Role of changes in arterial and ventricular elastance and ventriculo-arterial coupling
Jain D, Shaker S, Burg M, Wackers F, Zaret B. Mental stress induced left ventricular dysfunction: Role of changes in arterial and ventricular elastance and ventriculo-arterial coupling. Journal Of Nuclear Cardiology 1995, 2: s124. DOI: 10.1016/s1071-3581(05)80577-x.Peer-Reviewed Original Research
1993
Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial)
Berger P, Ruocco N, Ryan T, Jacobs A, Zaret B, Wackers F, Frederick M, Faxon D, Group R. Frequency and significance of right ventricular dysfunction during inferior wall left ventricular myocardial infarction treated with thrombolytic therapy (results from the Thrombolysis in Myocardial Infarction [TIMI] II trial). The American Journal Of Cardiology 1993, 71: 1148-1152. PMID: 8097614, DOI: 10.1016/0002-9149(93)90637-r.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAngioplasty, Balloon, CoronaryCombined Modality TherapyConstriction, PathologicCoronary VesselsFemaleHeart DiseasesHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionRadionuclide VentriculographyThrombolytic TherapyTissue Plasminogen ActivatorVentricular Function, LeftVentricular Function, RightConceptsRV wall motion abnormalitiesRight ventricular dysfunctionRV dysfunctionVentricular myocardial infarctionWall motion abnormalitiesVentricular dysfunctionThrombolytic therapyRadionuclide ventriculographyMyocardial infarctionMotion abnormalitiesInferior wallLower mean left ventricular ejection fractionMean left ventricular ejection fractionLeft ventricular ejection fractionBaseline clinical characteristicsInfarct-related arteryMyocardial Infarction (TIMI) II trialVentricular ejection fractionEquilibrium radionuclide ventriculographyHospital complicationsMultivessel diseaseII trialClinical characteristicsHospital dischargeEjection fraction
1990
Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction
Kayden D, Wackers F, Zaret B. Silent left ventricular dysfunction during routine activity after thrombolytic Therapy for acute myocardial infarction. Journal Of The American College Of Cardiology 1990, 15: 1500-1507. PMID: 2345230, DOI: 10.1016/0735-1097(90)92817-l.Peer-Reviewed Original ResearchConceptsTransient left ventricular dysfunctionLeft ventricular dysfunctionSilent left ventricular dysfunctionVentricular dysfunctionMyocardial infarctionCardiac eventsHospital dischargeEjection fractionThrombolytic therapySubmaximal supine bicycle exerciseNormal activityBaseline ejection fractionExercise test resultsSubsequent cardiac eventsSupine bicycle exerciseVentricular function monitoringAcute myocardial infarctionChest painPeak exerciseBicycle exerciseAmbulatory patientsElectrocardiographic changesPoor outcomePrognostic informationFunction monitoring
1989
Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease
LaVeau P, Rozanski A, Krantz D, Cornell C, Cattanach L, Zaret B, Wackers F. Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease. American Heart Journal 1989, 118: 1-8. PMID: 2741776, DOI: 10.1016/0002-8703(89)90064-1.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionCoronary artery diseaseCoronary diseaseMental stressArtery diseaseNormal volunteersPsychological stressVentricular ejection fractionStress-induced abnormalitiesLVEF responseChest painVentricular dysfunctionEjection fractionDouble productECG changesTransient ischemiaAcute decreaseBaseline valuesNormal subjectsStroop Color-Word TestPatientsPhysical exerciseAmbulatory monitoringImmediate reboundColor-Word Test
1987
Congestive heart failure and left ventricular dysfunction complicating doxorubicin therapy Seven-year experience using serial radionuclide angiocardiography
Schwartz R, McKenzie W, Alexander J, Sager P, D'Souza A, Manatunga A, Schwartz P, Berger H, Setaro J, Surkin L, Wackers F, Zaret B. Congestive heart failure and left ventricular dysfunction complicating doxorubicin therapy Seven-year experience using serial radionuclide angiocardiography. The American Journal Of Medicine 1987, 82: 1109-1118. PMID: 3605130, DOI: 10.1016/0002-9343(87)90212-9.Peer-Reviewed Original ResearchConceptsClinical congestive heart failureCongestive heart failureVentricular ejection fractionAbsolute left ventricular ejection fractionLeft ventricular ejection fractionHeart failureEjection fractionDoxorubicin therapyMild congestive heart failureClinical predictor variablesDiscontinuation of doxorubicinTotal cumulative dosageHigh-risk patientsHigh-risk subsetMajority of patientsHigh cumulative doseCommunity hospital settingProportional hazards regressionSeven-year experienceCommunity hospital environmentSerial radionuclideLast followVentricular dysfunctionClinical outcomesRoutine therapyRight ventricular myocardial infarction with anterior wall left ventricular infarction: An autopsy study
Cabin H, Clubb K, Wackers F, Zaret B. Right ventricular myocardial infarction with anterior wall left ventricular infarction: An autopsy study. American Heart Journal 1987, 113: 16-23. PMID: 3799430, DOI: 10.1016/0002-8703(87)90004-4.Peer-Reviewed Original ResearchConceptsRight ventricular myocardial infarctionVentricular myocardial infarctionAnterior myocardial infarctionMyocardial infarctionVentricular infarctionVentricular free wallRadionuclide angiographyVentricular infarctAnterior wallFree wallInferior left ventricular infarctionRight ventricular free wallRight ventricular dysfunctionRight ventricular infarctRight ventricular necrosisLeft ventricular infarctionLeft ventricular free wallEquilibrium radionuclide angiographyVentricular necrosisVentricular dysfunctionAutopsy studyGlobal dysfunctionInfarctionTherapeutic implicationsClinical importance
1982
Radionuclide Ventriculography
Wackers F, Berger H, Zaret B. Radionuclide Ventriculography. Developments In Cardiovascular Medicine 1982, 14: 199-233. DOI: 10.1007/978-94-009-7452-4_8.Peer-Reviewed Original ResearchEjection fractionMyocardial infarctFirst acute myocardial infarctLeft ventricular ejection fractionSeattle Heart WatchLeft ventricular dysfunctionCardiac enzyme releaseVentricular ejection fractionCoronary heart diseaseAcute myocardial infarctVentricular dysfunctionPathophysiologic insightsInfarct sizeRadionuclide ventriculographyVentricular performanceVentricular hemodynamicsHeart diseaseMyocardial necrosisValuable predictorEnzyme releaseInfarctsPatientsDirect correlationMorbidityPrognosis
1981
Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries.
Berger HJ, Sands MJ, Davies RA, Wackers FJ, Alexander J, Lachman AS, Williams BW, Zaret BL. Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Annals Of Internal Medicine 1981, 94: 186-91. PMID: 7469209, DOI: 10.7326/0003-4819-94-2-186.Peer-Reviewed Original ResearchConceptsNormal coronary arteriesLeft ventricular performanceChest painVentricular performanceCoronary arteryExercise electrocardiogramAbnormal ejection fraction responseMaximal upright bicycle exerciseCoronary arterial spasmUpright bicycle exerciseEjection fraction responseFirst-pass radionuclide angiocardiographyThallium-201 imagingErgonovine testingVentricular dysfunctionArterial spasmBicycle exerciseErgonovine provocationAdditional patientsTreadmill exercisePerfusion defectsRadionuclide angiocardiographyRegional dysfunctionPatientsFraction response
1978
Prevalence of right ventricular involvement in inferior wall infarction assessed with myocardial imaging with thallium-201 and technetium-99m pyrophosphate
Wackers F, Lie K, Sokole E, Res J, Van Der Schoot J, Durrer D. Prevalence of right ventricular involvement in inferior wall infarction assessed with myocardial imaging with thallium-201 and technetium-99m pyrophosphate. The American Journal Of Cardiology 1978, 42: 358-362. PMID: 210648, DOI: 10.1016/0002-9149(78)90928-1.Peer-Reviewed Original ResearchConceptsRight ventricular involvementAcute inferior wall infarctionInferior wall infarctionVentricular involvementThallium-201Myocardial imagingSevere right ventricular failurePump failurePositive pyrophosphate scansSevere pump failureRight ventricular failureSubgroup of patientsThallium-201 defectsPyrophosphate scanCardiogenic shockVentricular dysfunctionVentricular failureConsecutive patientsConsecutive seriesClassic signsPatientsClinical relevanceInfarctionNonivasive methodVolume loading