2004
Cardiac Abnormalities in Diabetic Patients With Neuropathy
Johnson BF, Nesto RW, Pfeifer MA, Slater WR, Vinik AI, Chyun DA, Law G, Wackers FJ, Young LH. Cardiac Abnormalities in Diabetic Patients With Neuropathy. Diabetes Care 2004, 27: 448-454. PMID: 14747227, DOI: 10.2337/diacare.27.2.448.Peer-Reviewed Original ResearchMeSH KeywordsAldehyde ReductaseBenzothiazolesCardiac OutputDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NeuropathiesDouble-Blind MethodEnzyme InhibitorsExercise TestFemaleHeartHeart Conduction SystemHeart RateHumansMaleMiddle AgedPhthalazinesPlacebosStroke VolumeThiazolesVentricular Function, LeftConceptsLeft ventricular ejection fractionDiabetic patientsARI treatmentCardiac outputStroke volumeCardiac abnormalitiesAldose reductase inhibitorExercise left ventricular ejection fractionAbnormal heart rate variabilityDiastolic peak filling rateAsymptomatic cardiac abnormalitiesGated radionuclide ventriculographyMaximal bicycle exercisePlacebo-treated subjectsDiastolic filling rateVentricular ejection fractionCoronary artery diseaseValvular heart diseasePeak filling rateExercise cardiac outputLV stroke volumeHeart rate variabilityBlinded treatmentInsulin useArtery disease
1995
Value of radionuclide rest and exercise left ventricular ejection fraction in assessing survival of patients after thrombolytic therapy for acute myocardial infarction: Results of thrombolysis in myocardial infarction (TIMI) phase II study
Zaret B, Wackers F, Terrin M, Forman S, Williams D, Knatterud G, Braunwald E, Group F. Value of radionuclide rest and exercise left ventricular ejection fraction in assessing survival of patients after thrombolytic therapy for acute myocardial infarction: Results of thrombolysis in myocardial infarction (TIMI) phase II study. Journal Of The American College Of Cardiology 1995, 26: 73-79. PMID: 7797778, DOI: 10.1016/0735-1097(95)00146-q.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionExercise left ventricular ejection fractionPeak exercise ejection fractionExercise ejection fractionEjection fractionAcute myocardial infarctionImportant prognostic indexThrombolytic therapyPrethrombolytic eraCardiac mortalityPrognostic indexPrognostic valueMyocardial infarctionMortality rateMyocardial Infarction Phase II (TIMI II) studyMyocardial Infarction trialRest ejection fractionSubmaximal supine exercisePhase II studySurvival of patientsResults of thrombolysisHigh mortality rateCause mortalityII study