2021
Screening for Lung Cancer CHEST Guideline and Expert Panel Report
Mazzone PJ, Silvestri GA, Souter LH, Caverly TJ, Kanne JP, Katki HA, Wiener RS, Detterbeck FC. Screening for Lung Cancer CHEST Guideline and Expert Panel Report. CHEST Journal 2021, 160: e427-e494. PMID: 34270968, PMCID: PMC8727886, DOI: 10.1016/j.chest.2021.06.063.Peer-Reviewed Original ResearchMeSH KeywordsDiagnostic Reference LevelsEarly Detection of CancerHumansLung NeoplasmsRadiologic HealthRisk AssessmentSmoking CessationTomography, X-Ray ComputedConceptsNational Lung Screening TrialLow-dose chest CTLung cancerCT screeningChest CTClinical questionsLow-dose CT screeningEvidence baseLow-dose chest CT screeningAdditional clinical questionsScreen-detected findingsScreening-eligible individualsGrading of RecommendationsChest CT screeningStandard of careImportant clinical questionsSystematic literature reviewExpert Panel ReportLow-dose CTCHEST GuidelineCessation interventionsCochrane LibraryGuideline publicationLiterature reviewConsensus statementExecutive Summary Screening for Lung Cancer: Chest Guideline and Expert Panel Report
Mazzone PJ, Silvestri GA, Souter LH, Caverly TJ, Kanne JP, Katki HA, Wiener RS, Detterbeck FC. Executive Summary Screening for Lung Cancer: Chest Guideline and Expert Panel Report. CHEST Journal 2021, 160: 1959-1980. PMID: 34270965, PMCID: PMC8727851, DOI: 10.1016/j.chest.2021.07.003.Peer-Reviewed Original ResearchConceptsNational Lung Screening TrialLow-dose chest CTLung cancerCT screeningChest CTClinical questionsLow-dose CT screeningEvidence baseLow-dose chest CT screeningAdditional clinical questionsScreen-detected findingsScreening-eligible individualsGrading of RecommendationsChest CT screeningStandard of careImportant clinical questionsSystematic literature reviewExpert Panel ReportLow-dose CTCHEST GuidelineCessation interventionsCochrane LibraryGuideline publicationLiterature reviewConsensus statement
2018
Screening for Lung Cancer CHEST Guideline and Expert Panel Report
Mazzone PJ, Silvestri GA, Patel S, Kanne JP, Kinsinger LS, Wiener RS, Hoo G, Detterbeck FC. Screening for Lung Cancer CHEST Guideline and Expert Panel Report. CHEST Journal 2018, 153: 954-985. PMID: 29374513, DOI: 10.1016/j.chest.2018.01.016.Peer-Reviewed Original ResearchConceptsLow-dose CT screeningLow-dose chest CTCT screeningChest CTClinical questionsNational Lung Screening TrialEvidence baseScreen-detected findingsLung cancer resultsChest CT screeningScreening-eligible patientsKey clinical questionsStandard of careImportant clinical questionsSystematic literature reviewExpert Panel ReportLow-dose CTCHEST GuidelineGRADE approachCessation interventionsCochrane LibraryLiterature reviewLung cancerPICO questionScreening Trial
2016
The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer
Travis WD, Asamura H, Bankier AA, Beasley MB, Detterbeck F, Flieder DB, Goo JM, MacMahon H, Naidich D, Nicholson AG, Powell CA, Prokop M, Rami-Porta R, Rusch V, van Schil P, Yatabe Y, Members I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E. The IASLC Lung Cancer Staging Project: Proposals for Coding T Categories for Subsolid Nodules and Assessment of Tumor Size in Part-Solid Tumors in the Forthcoming Eighth Edition of the TNM Classification of Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 1204-1223. PMID: 27107787, DOI: 10.1016/j.jtho.2016.03.025.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma in SituAdenocarcinoma of LungHumansLung NeoplasmsNeoplasm StagingTomography, X-Ray ComputedConceptsPart-solid tumorsLepidic predominant adenocarcinomaTumor sizeLung cancerInternational Cancer Control tumorEighth editionWorld Health Organization classificationIASLC Lung Cancer Staging ProjectLung Cancer Staging ProjectForthcoming Eighth EditionNonmucinous lung adenocarcinomasPrimary tumor categoryComputed tomography findingsInvasive mucinous adenocarcinomaSquamous cell carcinomaGround-glass componentInvasive sizeTomography findingsClinical stagingMucinous adenocarcinomaPathologic evaluationResected specimensTNM classificationCell carcinomaMetastasis classification
2015
Viewing Lung Cancer in Color Instead of Black and White
Detterbeck FC. Viewing Lung Cancer in Color Instead of Black and White. Annals Of The American Thoracic Society 2015, 12: 1118-9. PMID: 26317270, DOI: 10.1513/annalsats.201506-338ed.Peer-Reviewed Original ResearchAdenocarcinomaFemaleHumansLung NeoplasmsMaleMedical OverusePositron-Emission TomographyTomography, X-Ray ComputedComponents Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement
Mazzone P, Powell CA, Arenberg D, Bach P, Detterbeck F, Gould MK, Jaklitsch MT, Jett J, Naidich D, Vachani A, Wiener RS, Silvestri G. Components Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement. CHEST Journal 2015, 147: 295-303. PMID: 25356819, PMCID: PMC4502754, DOI: 10.1378/chest.14-2500.Peer-Reviewed Original ResearchMeSH KeywordsHealth PolicyHumansLung NeoplasmsMass ScreeningRisk AssessmentSolitary Pulmonary NoduleTomography, X-Ray ComputedConceptsLung cancer screening programsCancer screening programsLung cancer screeningAmerican Thoracic SocietyCancer screeningScreening programChest PhysiciansAmerican CollegeHigh-quality lung cancer screening programThoracic Oncology NetworkEvidence-based reviewLow-dose chest CT scansChest CT scanAmerican Cancer SocietyLung cancerComponents of screeningEssential program componentsThoracic SocietyOncology NetworkCancer SocietyCT scanProgram componentsPreventive oncologyAmerican SocietyScreening facility
2014
A Modern Definition of Mediastinal Compartments
Carter BW, Tomiyama N, Bhora FY, de Christenson M, Nakajima J, Boiselle PM, Detterbeck FC, Marom EM. A Modern Definition of Mediastinal Compartments. Journal Of Thoracic Oncology 2014, 9: s97-s101. PMID: 25396318, DOI: 10.1097/jto.0000000000000292.Peer-Reviewed Original ResearchMeSH KeywordsConsensusDiagnosis, DifferentialHumansMediastinal NeoplasmsMediastinumTomography, X-Ray ComputedConceptsInternational Thymic Malignancy Interest GroupProspective clinical trialsLateral chest radiographsParavertebral compartmentMediastinal massClinical trialsDifferential diagnosisChest radiographsSurgical proceduresClinical classificationMediastinal compartmentClinical casesAnatomic boundariesArbitrary landmarksCompartmentsMediastinumBiopsyApproaching the Patient with an Anterior Mediastinal Mass: A Guide for Radiologists
Carter BW, Okumura M, Detterbeck FC, Marom EM. Approaching the Patient with an Anterior Mediastinal Mass: A Guide for Radiologists. Journal Of Thoracic Oncology 2014, 9: s110-s118. PMID: 25396307, DOI: 10.1097/jto.0000000000000295.Peer-Reviewed Original ResearchClinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung
Detterbeck FC. Clinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung. Thoracic Surgery Clinics 2014, 24: 267-276. PMID: 25065927, DOI: 10.1016/j.thorsurg.2014.04.002.Peer-Reviewed Original ResearchMeSH KeywordsBiopsyCarcinoid TumorCarcinoma, BronchogenicDiagnosis, DifferentialHumansLungLung NeoplasmsNeuroendocrine TumorsTomography, X-Ray ComputedConceptsCell lung cancerCarcinoid tumorsLung cancerNeuroendocrine tumorsLimited biopsyNon-small cell lung cancerLarge cell neuroendocrine cancerMost non-small cell lung cancersSmall cell lung cancerPeripheral parenchymal lesionAtypical carcinoid tumorTypical carcinoid tumorNode enlargementEndobronchial tumorMediastinal tumorCharacteristic presentationClinical presentationParenchymal lesionsNeuroendocrine cancerRapid progressionTumorsCancerBiopsyLungPresentationOverdiagnosis during lung cancer screening: is it an overemphasised, underappreciated, or tangential issue?
Detterbeck FC. Overdiagnosis during lung cancer screening: is it an overemphasised, underappreciated, or tangential issue? Thorax 2014, 69: 408. PMID: 24646660, DOI: 10.1136/thoraxjnl-2014-205140.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungDiagnostic ErrorsFemaleHumansLung NeoplasmsMaleMass ScreeningTomography, X-Ray ComputedScreening for lung cancer: moving into a new era.
Detterbeck FC, Unger M. Screening for lung cancer: moving into a new era. Annals Of Internal Medicine 2014, 160: 363-4. PMID: 24379025, DOI: 10.7326/m13-2904.Peer-Reviewed Original Research
2013
Lung Cancer Screening: Response
Detterbeck FC, Bach PB. Lung Cancer Screening: Response. CHEST Journal 2013, 144: 1737-1738. PMID: 24189879, DOI: 10.1378/chest.13-1736.Peer-Reviewed Original ResearchTargeted CT Image Screening and Its Effect on Lung Cancer Detection Rate: Response
Detterbeck FC. Targeted CT Image Screening and Its Effect on Lung Cancer Detection Rate: Response. CHEST Journal 2013, 144: 1420-1421. PMID: 24081362, DOI: 10.1378/chest.13-1350.Peer-Reviewed Original ResearchClinical Statement on the Role of the Surgeon and Surgical Issues Relating to Computed Tomography Screening Programs for Lung Cancer∗
Rocco G, Allen MS, Altorki NK, Asamura H, Blum MG, Detterbeck FC, Dresler CM, Gossot D, Grondin SC, Jaklitsch MT, Mitchell JD, Newton JR, Van Schil PE, Waddell TK, Wood DE. Clinical Statement on the Role of the Surgeon and Surgical Issues Relating to Computed Tomography Screening Programs for Lung Cancer∗. The Annals Of Thoracic Surgery 2013, 96: 357-360. PMID: 23816098, DOI: 10.1016/j.athoracsur.2013.05.067.Peer-Reviewed Original ResearchMeSH KeywordsGlobal HealthHumansLung NeoplasmsMass ScreeningMorbidityReproducibility of ResultsThoracic Surgical ProceduresTomography, X-Ray ComputedThymoma: current diagnosis and treatment.
Detterbeck FC, Zeeshan A. Thymoma: current diagnosis and treatment. Chinese Medical Journal 2013, 126: 2186-91. PMID: 23769581, DOI: 10.3760/cma.j.issn.0366-6999.20130177.Peer-Reviewed Original ResearchMeSH KeywordsHumansIncidenceNeoplasm Recurrence, LocalNeoplasm StagingThymomaThymus NeoplasmsTomography, X-Ray ComputedConceptsComplete resectionInternational Thymic Malignancy Interest GroupMasaoka-Koga classificationMainstay of treatmentMajor prognostic factorAnterior mediastinal tumorTreatment of thymomaEarly-stage thymomaRare malignant tumorCore needle biopsyStandard diagnostic modalityFine-needle aspirationFormal systematic reviewMajor blood vesselsIVA tumorsPreoperative chemotherapyPrimary surgeryPostoperative radiationPrognostic factorsSurgical resectionThymic malignanciesMediastinal tumorMyasthenia gravisThymoma resectionIntravenous contrastMethods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC. Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e211s-e250s. PMID: 23649440, DOI: 10.1378/chest.12-2355.Peer-Reviewed Original ResearchConceptsLung cancerPET scanningNeedle techniqueCT scanningMediastinal metastasesMetastatic diseasePractice guidelinesAmerican CollegeChest Physicians Evidence-Based Clinical Practice GuidelinesTissue biopsiesChest Physicians Lung Cancer GuidelinesEvidence-based clinical practice guidelinesNon-small cell lung cancer diagnosisNon-small cell lung cancerMediastinal lymph node metastasisCell lung cancer diagnosisLung cancer guidelinesPET scan findingsLymph node metastasisCell lung cancerClinical practice guidelinesLymph node stationsUnsuspected metastatic diseaseEndobronchial ultrasound needle aspirationPET-CT scanningScreening for Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Detterbeck FC, Mazzone PJ, Naidich DP, Bach PB. Screening for Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e78s-e92s. PMID: 23649455, PMCID: PMC3749713, DOI: 10.1378/chest.12-2350.Peer-Reviewed Original ResearchMeSH KeywordsCounselingHumansLung NeoplasmsMass ScreeningRadiography, ThoracicRiskSmokingSputumTomography, X-Ray ComputedConceptsLung cancer deathsLung cancerCancer deathChest Physicians Evidence-Based Clinical Practice GuidelinesEvidence-based clinical practice guidelinesLow-dose CT screeningMajority of patientsRisk of complicationsClinical practice guidelinesLung cancer diagnosisSignificant reductionNumber of deathsLDCT screeningCurative treatmentLarge RCTsCT screeningTreatment recommendationsChest radiographsPractice guidelinesAmerican CollegeEffective treatmentElevated riskResult of screeningAdvanced stageSystematic reviewNational comprehensive cancer network.
Detterbeck F, Tanoue L, Reid A. National comprehensive cancer network. Journal Of The National Comprehensive Cancer Network 2013, 11: 365-6. PMID: 23584338, DOI: 10.6004/jnccn.2013.0050.Peer-Reviewed Original Research
2012
Benefits and Harms of CT Screening for Lung Cancer: A Systematic Review
Bach PB, Mirkin JN, Oliver TK, Azzoli CG, Berry DA, Brawley OW, Byers T, Colditz GA, Gould MK, Jett JR, Sabichi AL, Smith-Bindman R, Wood DE, Qaseem A, Detterbeck FC. Benefits and Harms of CT Screening for Lung Cancer: A Systematic Review. JAMA 2012, 307: 2418-2429. PMID: 22610500, PMCID: PMC3709596, DOI: 10.1001/jama.2012.5521.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesHumansLung NeoplasmsRadiation DosageRandomized Controlled Trials as TopicRiskRisk Reduction BehaviorTomography, X-Ray ComputedConceptsLow-dose computed tomographyLung cancer mortalityLung cancerLDCT screeningCancer deathCancer mortalityEffect of LDCTSystematic reviewNational Lung Screening TrialEvidence-based clinical guidelinesFrequency of followLung cancer deathsLung cancer screeningRisk of deathPotential harmAdvanced diseaseCause mortalityCohort studyMost patientsSecondary outcomesMajor complicationsPrimary outcomeRandomized studyRandomized trialsCT screeningCancer, concepts, cohorts and complexity: avoiding oversimplification of overdiagnosis
Detterbeck FC. Cancer, concepts, cohorts and complexity: avoiding oversimplification of overdiagnosis. Thorax 2012, 67: 842. PMID: 22628119, DOI: 10.1136/thoraxjnl-2012-201779.Peer-Reviewed Original Research