2017
Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
Korst RJ, Fernando S, Catlin AC, Rutledge JR, Girard N, Huang J, Detterbeck F, Database C. Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database. The Annals Of Thoracic Surgery 2017, 104: 1815-1820. PMID: 29033016, PMCID: PMC5785101, DOI: 10.1016/j.athoracsur.2017.06.053.Peer-Reviewed Original ResearchConceptsPositron emission tomographyInternational Thymic Malignancy Interest GroupHistologic typeThymic malignanciesPretreatment workupPathologic stageEmission tomographyProspective databaseThymic tumorsTumor stageMaximum standardized uptake valueProspective research databaseHistologic tumor typeThymic epithelial tumorsStandardized uptake valueCharacteristic curveAnalysis of receiverClinicopathologic featuresRare tumorEpithelial tumorsLarge cohortResearch DatabaseUptake valueTumor typesPatients
2013
A New Method to Predict Postoperative Lung Function: Quantitative Breath Sound Measurements
Detterbeck F, Gat M, Miller D, Force S, Chin C, Fernando H, Sonett J, Morice R. A New Method to Predict Postoperative Lung Function: Quantitative Breath Sound Measurements. The Annals Of Thoracic Surgery 2013, 95: 968-975. PMID: 23369350, DOI: 10.1016/j.athoracsur.2012.07.045.Peer-Reviewed Original ResearchMeSH KeywordsFollow-Up StudiesForced Expiratory VolumeHumansLungLung DiseasesPerfusion ImagingPneumonectomyPredictive Value of TestsProspective StudiesROC CurveVibrationConceptsPostoperative lung functionVibration response imagingLung functionLung resectionPPO valuesPostoperative pulmonary function testsPulmonary function testsRate of complicationsSingle-center studyCategorization of patientsPerfusion measurementsActual postoperative valuesRadiation-free methodRadiation-free alternativeLung malignancyLung scintigraphyFunction testsPostoperative valuesPatient assessmentRegional perfusionElevated riskPatientsLungPerfusion methodPerfusion
2012
Cancer, concepts, cohorts and complexity: avoiding oversimplification of overdiagnosis
Detterbeck FC. Cancer, concepts, cohorts and complexity: avoiding oversimplification of overdiagnosis. Thorax 2012, 67: 842. PMID: 22628119, DOI: 10.1136/thoraxjnl-2012-201779.Peer-Reviewed Original Research
2010
High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology
Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL, Syrigos KN. High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology. BMC Cancer 2010, 10: 186. PMID: 20459695, PMCID: PMC2875218, DOI: 10.1186/1471-2407-10-186.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedBiomarkers, TumorCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellCell DifferentiationCohort StudiesConnecticutFemaleGreeceHumansKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedNeoplasm StagingPredictive Value of TestsProportional Hazards ModelsProto-Oncogene Proteins c-bcl-2Reproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUp-RegulationConceptsNon-small cell lung cancer patientsCell lung cancer patientsNon-squamous tumorsLung cancer patientsBcl-2 expressionNSCLC patientsCancer patientsBcl-2Favorable outcomeIndependent cohortSmall cell lung cancer patientsIndependent lower riskNon-squamous histologySubgroup of patientsHigh expressersSquamous cell carcinomaHigh Bcl-2 expressionBcl-2 protein levelsSquamous histologyMedian survivalPrognostic factorsValidation cohortCell carcinomaPathological characteristicsPrognostic stratification
2004
Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer
Detterbeck FC, Vansteenkiste JF, Morris DE, Dooms CA, Khandani AH, Socinski MA. Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer. CHEST Journal 2004, 126: 1656-1666. PMID: 15539740, DOI: 10.1378/chest.126.5.1656.Peer-Reviewed Original ResearchMeSH KeywordsCombined Modality TherapyHumansLung NeoplasmsNeoplasm StagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsConceptsManagement of patientsLung cancerPET imagingCycles of chemotherapyCompletion of treatmentPossible lung cancerIntensity of uptakePositron emission tomography (PET) imagingEmission Tomography ImagingPositron emission tomographyFurther technologic improvementsInduction therapyPatient outcomesBiological aggressivenessPatientsEmission tomographyTechnologic improvementsTomography imagingStaging approachRadiotherapy treatment fieldCancerTreatment fieldImagingTreatmentPET imagesMultidisciplinary management of lung cancer.
Gould MK, Silvestri GA, Detterbeck F. Multidisciplinary management of lung cancer. New England Journal Of Medicine 2004, 350: 2008-10; author reply 2008-10. PMID: 15131841.Peer-Reviewed Original Research