2017
Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT
Gao SJ, Kim AW, Puchalski JT, Bramley K, Detterbeck FC, Boffa DJ, Decker RH. Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT. Lung Cancer 2017, 109: 36-41. PMID: 28577947, DOI: 10.1016/j.lungcan.2017.04.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungClinical Decision-MakingDiagnostic ImagingFemaleHumansLung NeoplasmsMaleMediastinumMiddle AgedNeoplasm MetastasisNeoplasm StagingPatient SelectionPositron Emission Tomography Computed TomographyPractice Guidelines as TopicRetrospective StudiesConceptsOccult N2 diseaseOccult N2 metastasesGround-glass componentInvasive mediastinal stagingCurative-intent therapyT2 tumorsN2 metastasisPET-CTInvasive stagingN2 diseaseT1 tumorsNegative predictive valueMediastinal stagingEarly non-small cell lung cancerExact testPredictive valueSolid tumorsNon-small cell lung cancerClinical stage I NSCLCN2 lymph nodesNode-negative NSCLCOccult nodal involvementPure-solid tumorsStage I NSCLCT1-2N0 disease
2014
Lung cancer staging: the value of PET depends on the clinical setting
Detterbeck FC, Figueroa Almanzar S. Lung cancer staging: the value of PET depends on the clinical setting. Journal Of Thoracic Disease 2014, 6: 1714-23. PMID: 25589964, PMCID: PMC4283348, DOI: 10.3978/j.issn.2072-1439.2014.11.16.Peer-Reviewed Original ResearchClinical settingEvaluation of patientsInvasive mediastinal stagingPositron emission tomography (PET) imagingEmission Tomography ImagingValue of PETInvasive stagingImpact of PETM1 diseaseN2 diseasePET findingsMediastinal stagingLung cancerRealist synthesis methodResectionClinical contextTomography imagingPatientsRCTsEvaluation of differencesHigher chanceStagingInconsistent resultsDiseaseTraditional imagingManagement of Clinical Stage IIIA Primary Lung Cancers in the National Cancer Database
Hancock J, Rosen J, Moreno A, Kim AW, Detterbeck FC, Boffa DJ. Management of Clinical Stage IIIA Primary Lung Cancers in the National Cancer Database. The Annals Of Thoracic Surgery 2014, 98: 424-432. PMID: 24929895, DOI: 10.1016/j.athoracsur.2014.04.067.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerNational Cancer DatabaseClinical stagingMediastinal stagingLung cancerCancer DatabaseClinical stage IIIA non-small cell lung cancerStage IIIA non-small cell lung cancerIIIA non-small cell lung cancerTreatment approachesMediastinal lymph node diseaseMediastinal lymph node metastasisClinical N2 statusTreatment-naïve patientsLymph node diseasePrimary lung cancerUse of surgeryIIIA NSCLC patientsLymph node metastasisCell lung cancerOptimal treatment approachCommon treatment approachNaïve patientsUntreated patientsMediastinal lymph
2012
Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer
Vest MT, Tanoue L, Soulos PR, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2012, 7: 188-195. PMID: 22134069, PMCID: PMC3253367, DOI: 10.1097/jto.0b013e318236ecbb.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiopsy, NeedleCarcinoma, Non-Small-Cell LungCohort StudiesComorbidityConfidence IntervalsGuideline AdherenceHumansLung NeoplasmsLymph NodesMediastinoscopyMediastinumMedicareMultivariate AnalysisNeoplasm StagingOdds RatioPositron-Emission TomographySEER ProgramSurvival AnalysisUnited StatesConceptsStage IIIA non-small cell lung cancerIIIA non-small cell lung cancerNon-small cell lung cancerInvasive stagingCell lung cancerMediastinal stagingLung cancerClinical stage IIIA non-small cell lung cancerEnd Results-Medicare databaseStage IIIA NSCLC patientsPositron emission tomography scanningPathologic lymph nodesIIIA NSCLC patientsMultivariable logistic regressionInvasive mediastinal stagingNSCLC patientsOlder patientsPatient characteristicsLymph nodesPatient factorsHistologic confirmationPractice patternsMedicare claimsMedicare beneficiariesPET scanning
2010
Classification of the Thoroughness of Mediastinal Staging of Lung Cancer
Detterbeck F, Puchalski J, Rubinowitz A, Cheng D. Classification of the Thoroughness of Mediastinal Staging of Lung Cancer. CHEST Journal 2010, 137: 436-442. PMID: 20133290, DOI: 10.1378/chest.09-1378.Books
2009
Thoracoscopic versus open lobectomy debate: the pro argument
Detterbeck F. Thoracoscopic versus open lobectomy debate: the pro argument. Thoracic Surgical Science 2009, 6: doc04. PMID: 21289905, PMCID: PMC3011293, DOI: 10.3205/tss000018.Peer-Reviewed Original ResearchVATS lobectomyLung cancerLarge randomized trialsConfidence intervalsRate of deathAbility of patientsLong-term survivalAdjuvant chemotherapyForrest plotsMajor bleedingMinor endpointsPulmonary complicationsPostoperative painBlood transfusionOperative timeRandomized trialsLess painMediastinal stagingOpen lobectomyFunctional outcomeTumor stageNodal stationsClinical trialsOdds ratioLobectomy
2007
Integration of Mediastinal Staging Techniques for Lung Cancer
Detterbeck FC. Integration of Mediastinal Staging Techniques for Lung Cancer. Seminars In Thoracic And Cardiovascular Surgery 2007, 19: 217-224. PMID: 17983948, DOI: 10.1053/j.semtcvs.2007.07.011.Peer-Reviewed Original Research
2004
Seeking a Home for a PET, Part 2 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Staging of Patients With Suspected Lung Cancer
Detterbeck FC, Falen S, Rivera MP, Halle JS, Socinski MA. Seeking a Home for a PET, Part 2 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Staging of Patients With Suspected Lung Cancer. CHEST Journal 2004, 125: 2300-2308. PMID: 15189955, DOI: 10.1378/chest.125.6.2300.Peer-Reviewed Original ResearchConceptsPositron emission tomographyLung cancerPET imagingClinical evaluationPET uptakeClinical stage I lung cancerStage I lung cancerStage III lung cancerEmission tomographyI lung cancerStrong clinical signsPositive PET resultsStaging of patientsInvasive mediastinal stagingNegative clinical evaluationExtrathoracic stagingMetastatic diseaseMediastinal stagingPrimary lesionClinical signsPET resultsPatientsCancerStagingDefinite role