Insulin-like Growth Factor I Regulation of Swarm Rat Chondrosarcoma Chondrocytes in Culture
Seong S, Matsumura T, Lee F, Whelan M, Li X, Trippel S. Insulin-like Growth Factor I Regulation of Swarm Rat Chondrosarcoma Chondrocytes in Culture. Experimental Cell Research 1994, 211: 238-244. PMID: 8143769, DOI: 10.1006/excr.1994.1083.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCartilageChondrosarcomaCulture MediaDNA, NeoplasmGlycosaminoglycansInsulin-Like Growth Factor IRatsSulfatesThymidineTumor Cells, CulturedConceptsContribution of IGFDose-dependent fashionSwarm rat chondrosarcoma chondrocytesI antibodiesRat chondrosarcoma chondrocytesNonspecific antibodyFetal calf serumInsulin-like growth factor actionCalf serumInsulin-like growth factor IInsulin-like growth factor I regulationInhibitory effectChondrosarcoma chondrocytesRole of IGFIGF-I actionPresence of IGFEfficacy of IGFGrowth factor IMinimal inhibitory effectSerum-free controlsPost-natal lifeHalf-maximal stimulationEpiphyseal growth plateGrowth factor actionSerum concentrations