Systemic Parathyroid Hormone Enhances Fracture Healing in Multiple Murine Models of Type 2 Diabetes Mellitus
Alder K, White A, Chung Y, Lee I, Back J, Kwon H, Cahill S, Hao Z, Li L, Chen F, Lee S, Riedel M, Lee F. Systemic Parathyroid Hormone Enhances Fracture Healing in Multiple Murine Models of Type 2 Diabetes Mellitus. JBMR Plus 2020, 4: e10359. PMID: 32382692, PMCID: PMC7202418, DOI: 10.1002/jbm4.10359.Peer-Reviewed Original ResearchRisk of fractureFracture healingMurine modelType 2 diabetes mellitusPTH expressionEffects of hPTHIntermittent systemic administrationSuitable murine modelPrevalence of T2DMAge-related osteoporosisDiabetes mellitusPresent studySystemic administrationSkeletal fragilityMultisystemic diseaseT2DMOsteoporotic phenotypeBone qualityBone fracturesCalcium homeostasisMesenchymal stem cellsBone phenotypeHormone productionHPTHHealing