2007
Efficacy of Denileukin Diftitox in Subcutaneous Panniculitis-Like T-Cell Lymphoma
Hathaway T, Subtil A, Kuo P, Foss F. Efficacy of Denileukin Diftitox in Subcutaneous Panniculitis-Like T-Cell Lymphoma. Clinical Lymphoma Myeloma & Leukemia 2007, 7: 541-545. PMID: 18021473, DOI: 10.3816/clm.2007.n.040.Peer-Reviewed Original ResearchConceptsT-cell phenotypeDenileukin diftitoxSubcutaneous panniculitis-like T-cell lymphomaPanniculitis-like T-cell lymphomaSubcutaneous panniculitis-like lymphomaSystemic multi-agent chemotherapyAddition of bexaroteneMedian response durationMulti-agent chemotherapyComplete clinical regressionBone marrow transplantationT-cell lymphomaPleomorphic lymphocytesImmunosuppressive therapyRefractory patientsClinical regressionClinical responseMost patientsMarrow transplantationAggressive diseasePrognostic significanceDisease progressionRadiation therapyTraditional therapiesResponse duration
2002
Transformation in mycosis fungoides: The role of methotrexate
Abd-el-Baki J, Demierre MF, Li N, Foss FM. Transformation in mycosis fungoides: The role of methotrexate. Journal Of Cutaneous Medicine And Surgery 2002, 6: 109-116. PMID: 11992182, DOI: 10.1007/s10227-001-0040-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCell Transformation, NeoplasticDermatologic AgentsFemaleGenes, T-Cell Receptor gammaHumansImmunophenotypingImmunosuppressive AgentsLymphoma, Large B-Cell, DiffuseMaleMethotrexateMiddle AgedMycosis FungoidesPolymerase Chain ReactionRetrospective StudiesSkin NeoplasmsSurvival AnalysisConceptsLarge cell lymphomaRole of methotrexateMycosis fungoidesCell lymphomaDominant T-cell cloneCutaneous lymphoma databaseT cell clonesIncidence of transformationLymphoma databaseImmunosuppressive therapyMTX groupMTX exposureShort followupMulticenter studyResultsA totalRisk factorsSkin biopsiesRare disorderHigh incidencePatientsAdvanced stageMethotrexateConclusionOur resultsSignificant associationSkin specimens