2007
Deficiency in Inhibitory Cortical Interneurons Associates with Hyperactivity in Fibroblast Growth Factor Receptor 1 Mutant Mice
Smith K, Fagel DM, Stevens HE, Rabenstein RL, Maragnoli ME, Ohkubo Y, Picciotto MR, Schwartz ML, Vaccarino FM. Deficiency in Inhibitory Cortical Interneurons Associates with Hyperactivity in Fibroblast Growth Factor Receptor 1 Mutant Mice. Biological Psychiatry 2007, 63: 953-962. PMID: 17988653, DOI: 10.1016/j.biopsych.2007.09.020.Peer-Reviewed Original ResearchMeSH KeywordsAmphetamineAnimalsBehavior, AnimalBiogenic MonoaminesCell CountCentral Nervous System StimulantsCerebral CortexDisease Models, AnimalDopamine AgentsExploratory BehaviorFibroblast Growth Factor 1Glutamate DecarboxylaseHyperkinesisLocomotionMaleMethylphenidateMiceMice, KnockoutMotor ActivityNerve Tissue ProteinsNeural InhibitionNeuronsSignal TransductionConceptsInhibitory cortical circuitsCortical pyramidal neuronsD2 receptor antagonistGrowth factor receptor 1Spontaneous locomotor hyperactivityFibroblast growth factor receptor 1Factor receptor 1Inhibitory neuronal subtypesLocomotor hyperactivityDopamine agonistsCerebral cortexPyramidal neuronsBasal gangliaMotor hyperactivityReceptor antagonistInhibitory interneuronsTyrosine hydroxylaseCortical circuitsPsychiatric disordersLocomotor responseNeuronal subtypesReceptor 1Mutant miceDopamine transporterSpatial learning
1988
Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides.
Alho H, Ferrarese C, Vicini S, Vaccarino F. Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides. Brain Research 1988, 467: 193-204. PMID: 3378169, DOI: 10.1016/0165-3806(88)90023-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCarrier ProteinsCells, CulturedCerebral CortexDiazepam Binding InhibitorElectrophysiologyGABA Plasma Membrane Transport ProteinsGamma-Aminobutyric AcidGlutamate DecarboxylaseMembrane ProteinsMembrane Transport ProteinsNerve Tissue ProteinsNeuronsNeuropeptidesOrganic Anion TransportersPeptide FragmentsRatsConceptsGlutamic acid decarboxylaseNeuropeptide YGABAergic propertiesCerebral cortexGAD immunoreactivityGABA-modulinNeonatal cortical neuronsPrimary culturesInhibitory synaptic currentsDouble-labeling studiesBenzodiazepine recognition sitesGABA receptor modulatorsUseful experimental modelDays of cultureNeuroregulatory peptideGABAergic neuronsGABAergic neurotransmissionSpontaneous excitatoryNeonatal ratsCortical neuronsReceptor modulatorsLower incidenceTyrosine hydroxylaseSynaptic currentsCultured neurons