1985
gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]- t-butylbicyclophosphorothionate binding to cerebellar granule cells
Gallo V, Wise BC, Vaccarino F, Guidotti A. gamma-Aminobutyric acid- and benzodiazepine-induced modulation of [35S]- t-butylbicyclophosphorothionate binding to cerebellar granule cells. Journal Of Neuroscience 1985, 5: 2432-2438. PMID: 4032005, PMCID: PMC6565307, DOI: 10.1523/jneurosci.05-09-02432.1985.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidIntact cerebellar granule cellsCerebellar granule cellsGranule cellsT-butylbicyclophosphorothionateEffects of muscimolDose-dependent fashionAbsence of diazepamNeuroblastoma cell linesBenzodiazepine receptor ligandsSpecific bindingMicroM diazepamConvulsant activityCerebellar astrocytesMuscimolDiazepamLocke's solutionTotal radioactivityPrimary culturesReceptor ligandsCell linesReceptor complexCarboxylic acid methylesterInhibitionCells
1983
Loss of Purkinje cell‐associated benzodiazepine receptors spares a high affinity subpopulation: A study with pcd mutant mice
Vaccarino FM, Ghetti B, Wade SE, Rea MA, Aprison MH. Loss of Purkinje cell‐associated benzodiazepine receptors spares a high affinity subpopulation: A study with pcd mutant mice. Journal Of Neuroscience Research 1983, 9: 311-323. PMID: 6304330, DOI: 10.1002/jnr.490090308.Peer-Reviewed Original ResearchConceptsPopulation of receptorsBZ receptorsBenzodiazepine receptorsPurkinje cellsMutant miceHigh affinity subpopulationPcd miceGranule cell lossPurkinje cell degeneration mutant micePcd mutant miceNumber of receptorsDays of ageControl miceGlial cellsGranule cellsCell lossMicePcd mutantsReceptorsLow affinity sitesRegression analysisAgeDaysCellsSaturation data