Abstract 12593: Type 2 Diabetes Mellitus Polygenic Score Predicts New Onset Diabetes in Patients With Established Atherosclerotic Cardiovascular Disease: A FOURIER Sub-Study
Moura F, Kamanu F, Wiviott S, Giugliano R, Florez J, Roselli C, Keech A, Lubitz S, Ellinor P, Ruff C, Marston N, Sabatine M. Abstract 12593: Type 2 Diabetes Mellitus Polygenic Score Predicts New Onset Diabetes in Patients With Established Atherosclerotic Cardiovascular Disease: A FOURIER Sub-Study. Circulation 2022, 146: a12593-a12593. DOI: 10.1161/circ.146.suppl_1.12593.Peer-Reviewed Original ResearchNew-onset T2DPolygenic scoresGenetic riskClinical risk factorsAtherosclerotic cardiovascular diseaseGenome-wide significant single nucleotide polymorphismsGenetic risk categoriesAmerican Diabetes Association definitionRisk factorsCardiovascular diseaseSignificant single nucleotide polymorphismsPredicting new-onset diabetesBMI levelsNew-onset diabetes casesAssociation definitionType 2 diabetesNormal weightBaseline ageDiabetes casesNew-onset diabetesPre-diabetesSub-studySingle nucleotide polymorphismsBMIT2D