2019
P4626Neuronal nitric oxide sintetase polymorphism increases sympathetic activity and recurrent cardiovascular events after myocardial infarction
Oliveira E, Munhoz D, Carvalho L, Moura F, Machado-Silva W, Figueiredo V, Nobrega O, Sposito A. P4626Neuronal nitric oxide sintetase polymorphism increases sympathetic activity and recurrent cardiovascular events after myocardial infarction. European Heart Journal 2019, 40: ehz745.1008. DOI: 10.1093/eurheartj/ehz745.1008.Peer-Reviewed Original ResearchST-elevation myocardial infarctionMajor cardiovascular eventsT allele carriersFlow-mediated dilationRecurrent major cardiovascular eventsCardiovascular eventsSympathetic activityClinical impactT alleleAcute phase of ST-elevation myocardial infarctionAssociated with increased sympathetic toneDecreased FMDMyocardial infarctionClinical follow-upCox regression analysisIncreased sympathetic activityNitric oxideRecurrent cardiovascular eventsAutonomic nervous system modulationCardiac sudden deathElevation myocardial infarctionDecreased parasympathetic activityPeripheral nervous systemSimvastatin doseSympathetic tone
2015
Neuronal nitric oxide synthase polymorphism reduces endothelial function, increases sympathetic activity and recurrent cardiovascular events after myocardial infarction
Oliveira E, Munhoz D, Carvalho L, Moura F, Silva W, Figueiredo V, Coelho O, Nobrega O, Sposito A. Neuronal nitric oxide synthase polymorphism reduces endothelial function, increases sympathetic activity and recurrent cardiovascular events after myocardial infarction. BBA Clinical 2015, 3: s4-s5. DOI: 10.1016/j.bbacli.2015.05.013.Peer-Reviewed Original ResearchIncreased sympathetic activity