2024
Evaluating Treatment Patterns and the Role of Neoadjuvant Chemotherapy in Plasmacytoid Urothelial Carcinoma: Insights from a Combined National and Institutional Series
Rahman S, Kong V, Jalfon M, Hesse D, Kim J, Wright J, Adeniran A, Humphrey P, Martin D, Ghali F. Evaluating Treatment Patterns and the Role of Neoadjuvant Chemotherapy in Plasmacytoid Urothelial Carcinoma: Insights from a Combined National and Institutional Series. Cancers 2024, 16: 3050. PMID: 39272908, PMCID: PMC11394101, DOI: 10.3390/cancers16173050.Peer-Reviewed Original ResearchPlasmacytoid urothelial carcinomaMedian overall survivalNeoadjuvant chemotherapyUrothelial carcinomaOverall survivalTreatment patternsReceipt of neoadjuvant chemotherapyResponse to current therapiesCharacterize treatment patternsCox proportional hazards analysisEvaluate treatment patternsSite of metastasisProportional hazards analysisPT0 rateOS benefitHistological subtypesClinical stageCurrent therapiesInstitutional experiencePrimary outcomeNCDBTreatment trendsEffective treatmentPatientsCarcinoma
2023
Metastatic Bladder Cancer Expression and Subcellular Localization of Nectin-4 and Trop-2 in Variant Histology: A Rapid Autopsy Study
Ghali F, Vakar-Lopez F, Roudier M, Garcia J, Arora S, Cheng H, Schweizer M, Haffner M, Lee J, Yu E, Grivas P, Montgomery B, Hsieh A, Wright J, Lam H. Metastatic Bladder Cancer Expression and Subcellular Localization of Nectin-4 and Trop-2 in Variant Histology: A Rapid Autopsy Study. Clinical Genitourinary Cancer 2023, 21: 669-678. PMID: 37344281, PMCID: PMC10674028, DOI: 10.1016/j.clgc.2023.05.014.Peer-Reviewed Original ResearchConceptsMetastatic urothelial carcinomaVariant histologySacituzumab govitecanTrop-2Nectin-4Antibody-drug conjugatesMetastatic lesionsADC targetCytoplasmic stainingProminent cytoplasmic stainingMembrane stainingTrop-2 expressionCytoplasmic protein expressionMetastatic sitesAutopsy studyUrothelial carcinomaMetastatic tumorsSquamous differentiationClinical relevanceCancer expressionHistologyNeuroendocrineProtein expressionMRNA levelsProtein levels
2021
MP66-15 PATIENT-CENTRIC 3 DIMENSIONAL-BIOSYSTEMS FOR DEVELOPING PERSONALIZED IMMUNOTHERAPY FOR PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA
Lee S, Muldong M, Hsu J, Ghali F, Kang S, Kader A, Salmasi A, Jamieson C. MP66-15 PATIENT-CENTRIC 3 DIMENSIONAL-BIOSYSTEMS FOR DEVELOPING PERSONALIZED IMMUNOTHERAPY FOR PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA. Journal Of Urology 2021, 206: e1135-e1135. DOI: 10.1097/ju.0000000000002106.15.Peer-Reviewed Original Research
2020
161 Safety profile of robotic vs. laparoscopic radical nephroureterectomy for upper tract urothelial carcinoma: Data from the Robotic Surgery for Upper Tract Urothelial Cancer Study (ROBUUST) collaborative group
Veccia A, Steward J, Derweesh I, Margulis V, Uzzo R, Abdollah F, Minervini A, Cacciamani G, Mottrie A, Simone G, Rha K, Eun D, Mehrazin R, Gonzalgo M, Ghali F, Meng X, Srivastava A, Jamil M, Tellini R, Aron M, Mazzone E, Al-Qathani A, Asghar A, Sundaram C, Autorino R. 161 Safety profile of robotic vs. laparoscopic radical nephroureterectomy for upper tract urothelial carcinoma: Data from the Robotic Surgery for Upper Tract Urothelial Cancer Study (ROBUUST) collaborative group. European Urology Open Science 2020, 19: e316-e318. DOI: 10.1016/s2666-1683(20)32769-5.Peer-Reviewed Original Research164 Robotic radical nephroureterectomy for upper tract urothelial carcinoma: Data from the ROBotic surgery for Upper tract Urothelial cancer STudy (ROBUUST) collaborative group
Veccia A, Steward J, Derweesh I, Margulis V, Uzzo R, Abdollah F, Minervini A, Cacciamani G, Mottrie A, Simone G, Rha K, Eun D, Mehrazin R, Gonzalgo M, Ghali F, Meng X, Srivastava A, Jamil M, Riccardo T, Aron M, Mazzone E, Al-Qathani A, Asghar A, Sundaram C, Autorino R. 164 Robotic radical nephroureterectomy for upper tract urothelial carcinoma: Data from the ROBotic surgery for Upper tract Urothelial cancer STudy (ROBUUST) collaborative group. European Urology Open Science 2020, 19: e322-e324. DOI: 10.1016/s2666-1683(20)32772-5.Peer-Reviewed Original Research
2019
Diagnosis, management, and follow-up of upper tract urothelial carcinoma: an interdisciplinary collaboration between urology and radiology
Roberts J, Ghali F, Aganovic L, Bechis S, Healy K, Rivera-Sanfeliz G, Autorino R, Derweesh I. Diagnosis, management, and follow-up of upper tract urothelial carcinoma: an interdisciplinary collaboration between urology and radiology. Abdominal Radiology 2019, 44: 3893-3905. PMID: 31701194, DOI: 10.1007/s00261-019-02293-9.Peer-Reviewed Original ResearchConceptsUpper tract urothelial carcinomaUrothelial carcinomaDevelopment of UTUCPost-operative surveillanceRadical extirpative surgeryHigh recurrence rateSpecific clinical situationsMorbid therapyInvasive workupUrothelial malignancyRecurrence rateExtirpative surgeryLethal malignancyNew patientsInvasive proceduresClinical situationsEndoscopic surgeryEnvironmental exposuresDiagnosisPatientsSurgeryCarcinomaMalignancyWorkupClose working relationship